Inflammatory myofibroblastic tumour of the jaw: A rare presentation

Luis Monteiro; Manar Alhassani; Tiago Resende; Rui Albuquerque

doi:10.1016/j.jormas.2019.02.017

Inflammatory myofibroblastic tumour of the jaw: A rare presentation

Luis Monteiro, Manar Alhassani^*, Tiago Resende, Rui Albuquerque

^*Corresponding author for this work

Centre for Oral, Clinical & Translational Sciences

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Abstract

Inflammatory Myofibroblastic Tumour (IMT) is a rare entity of unknown aetiology and pathogenesis. It was initially described in the lung, although there have been reported cases affecting extra-pulmonary sites. The aetiology of IMT remains unclear, with current evidence suggesting that IMTs are neoplastic processes resulting from chromosomal translocations that often cause an overexpression of ALK tyrosine kinase. Histologically, a variably cellular myxoid morphology is common in these tumours, with the presence of inflammatory cell infiltrate. Clinically, symptoms are non-specific, although the presence of a swelling is frequently reported. Imaging studies are not very useful in the diagnosis, as they only describe the presence of a mass, and do not provide a definitive diagnosis. This article presents a case, of Inflammatory Myofibroblastic Tumour of the jaw, in a male patient aged 16 years.

Original language	English
Pages (from-to)	90-94
Number of pages	5
Journal	Journal of Stomatology, Oral and Maxillofacial Surgery
Volume	121
Issue number	1
DOIs	https://doi.org/10.1016/j.jormas.2019.02.017
Publication status	Published - Feb 2020

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title = "Inflammatory myofibroblastic tumour of the jaw: A rare presentation",

abstract = "Inflammatory Myofibroblastic Tumour (IMT) is a rare entity of unknown aetiology and pathogenesis. It was initially described in the lung, although there have been reported cases affecting extra-pulmonary sites. The aetiology of IMT remains unclear, with current evidence suggesting that IMTs are neoplastic processes resulting from chromosomal translocations that often cause an overexpression of ALK tyrosine kinase. Histologically, a variably cellular myxoid morphology is common in these tumours, with the presence of inflammatory cell infiltrate. Clinically, symptoms are non-specific, although the presence of a swelling is frequently reported. Imaging studies are not very useful in the diagnosis, as they only describe the presence of a mass, and do not provide a definitive diagnosis. This article presents a case, of Inflammatory Myofibroblastic Tumour of the jaw, in a male patient aged 16 years.",

author = "Luis Monteiro and Manar Alhassani and Tiago Resende and Rui Albuquerque",

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AU - Monteiro, Luis

AU - Alhassani, Manar

AU - Resende, Tiago

AU - Albuquerque, Rui

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AB - Inflammatory Myofibroblastic Tumour (IMT) is a rare entity of unknown aetiology and pathogenesis. It was initially described in the lung, although there have been reported cases affecting extra-pulmonary sites. The aetiology of IMT remains unclear, with current evidence suggesting that IMTs are neoplastic processes resulting from chromosomal translocations that often cause an overexpression of ALK tyrosine kinase. Histologically, a variably cellular myxoid morphology is common in these tumours, with the presence of inflammatory cell infiltrate. Clinically, symptoms are non-specific, although the presence of a swelling is frequently reported. Imaging studies are not very useful in the diagnosis, as they only describe the presence of a mass, and do not provide a definitive diagnosis. This article presents a case, of Inflammatory Myofibroblastic Tumour of the jaw, in a male patient aged 16 years.

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Inflammatory myofibroblastic tumour of the jaw: A rare presentation

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