Initiation to end point: the multiple roles of fibroblast growth factors in neural development

TY - JOUR

T1 - Initiation to end point: the multiple roles of fibroblast growth factors in neural development

AU - Mason, I

PY - 2007/8

Y1 - 2007/8

N2 - From a wealth of experimental findings, derived from both in vitro and in vivo experiments, it is becoming clear that fibroblast growth factors regulate processes that are central to all aspects of nervous system development. Some of these functions are well known, whereas others, such as the roles of these proteins in axon guidance and synaptogenesis, have been established only recently. The emergent picture is one of remarkable economy, in which this family of ligands is deployed and redeployed at successive developmental stages to sculpt the nervous system

AB - From a wealth of experimental findings, derived from both in vitro and in vivo experiments, it is becoming clear that fibroblast growth factors regulate processes that are central to all aspects of nervous system development. Some of these functions are well known, whereas others, such as the roles of these proteins in axon guidance and synaptogenesis, have been established only recently. The emergent picture is one of remarkable economy, in which this family of ligands is deployed and redeployed at successive developmental stages to sculpt the nervous system

U2 - 10.1038/nrn2189

DO - 10.1038/nrn2189

M3 - Literature review

VL - 8

SP - 583

EP - 596

JO - NATURE REVIEWS NEUROSCIENCE

JF - NATURE REVIEWS NEUROSCIENCE

IS - 8

ER -