Interstitial lung disease: a review of classification, etiology, epidemiology, clinical diagnosis, pharmacological and non-pharmacological treatment

TY - JOUR

T1 - Interstitial lung disease

T2 - a review of classification, etiology, epidemiology, clinical diagnosis, pharmacological and non-pharmacological treatment

AU - Althobiani, Malik A

AU - Russell, Anne-Marie

AU - Jacob, Joseph

AU - Ranjan, Yatharth

AU - Folarin, Amos A

AU - Hurst, John R

AU - Porter, Joanna C

N1 - Publisher Copyright: Copyright © 2024 Althobiani, Russell, Jacob, Ranjan, Folarin, Hurst and Porter.

PY - 2024

Y1 - 2024

N2 - Interstitial lung diseases (ILDs) refer to a heterogeneous and complex group of conditions characterized by inflammation, fibrosis, or both, in the interstitium of the lungs. This results in impaired gas exchange, leading to a worsening of respiratory symptoms and a decline in lung function. While the etiology of some ILDs is unclear, most cases can be traced back to factors such as genetic predispositions, environmental exposures (including allergens, toxins, and air pollution), underlying autoimmune diseases, or the use of certain medications. There has been an increase in research and evidence aimed at identifying etiology, understanding epidemiology, improving clinical diagnosis, and developing both pharmacological and non-pharmacological treatments. This review provides a comprehensive overview of the current state of knowledge in the field of interstitial lung diseases.

AB - Interstitial lung diseases (ILDs) refer to a heterogeneous and complex group of conditions characterized by inflammation, fibrosis, or both, in the interstitium of the lungs. This results in impaired gas exchange, leading to a worsening of respiratory symptoms and a decline in lung function. While the etiology of some ILDs is unclear, most cases can be traced back to factors such as genetic predispositions, environmental exposures (including allergens, toxins, and air pollution), underlying autoimmune diseases, or the use of certain medications. There has been an increase in research and evidence aimed at identifying etiology, understanding epidemiology, improving clinical diagnosis, and developing both pharmacological and non-pharmacological treatments. This review provides a comprehensive overview of the current state of knowledge in the field of interstitial lung diseases.

UR - http://www.scopus.com/inward/record.url?scp=85191836375&partnerID=8YFLogxK

U2 - 10.3389/fmed.2024.1296890

DO - 10.3389/fmed.2024.1296890

M3 - Review article

C2 - 38698783

SN - 2296-858X

VL - 11

SP - 1296890

JO - Frontiers in Medicine

JF - Frontiers in Medicine

M1 - 1296890

ER -