Intervention for Infants at Risk of Developing Autism: A Case Series

Jonathan Green; Ming Wai Wan; Jeanne Guiraud; Samina Holsgrove; Janet McNally; Vicky Slonims; Mayada Elsabbagh; Tony Charman; Andrew Pickles; Mark Johnson; The BASIS Team

doi:10.1007/s10803-013-1797-8

Intervention for Infants at Risk of Developing Autism: A Case Series

Jonathan Green, Ming Wai Wan, Jeanne Guiraud, Samina Holsgrove, Janet McNally, Vicky Slonims, Mayada Elsabbagh, Tony Charman, Andrew Pickles, Mark Johnson, The BASIS Team

Research output: Contribution to journal › Article › peer-review

71 Citations (Scopus)

Abstract

Theory and evidence suggest the potential value of prodromal intervention for infants at risk of developing autism. We report an initial case series (n = 8) of a parent-mediated, video-aided and interaction-focused intervention with infant siblings of autistic probands, beginning at 8-10 months of age. We outline the theory and evidence base behind this model and present data on feasibility, acceptability and measures ranging from parent-infant social interaction, to infant atypical behaviors, attention and cognition. The intervention proves to be both feasible and acceptable to families. Measurement across domains was successful and on larger samples promise to be an effective test of whether such an intervention in infancy will modify emergent atypical developmental trajectories in infants at risk for autism.

Original language	English
Pages (from-to)	2502-2514
Number of pages	13
Journal	Journal of Autism and Developmental Disorders
Volume	43
Issue number	11
DOIs	https://doi.org/10.1007/s10803-013-1797-8
Publication status	Published - Nov 2013

Access to Document

10.1007/s10803-013-1797-8

Cite this

@article{459bfba91bf442c8add6d630d522e14a,

title = "Intervention for Infants at Risk of Developing Autism: A Case Series",

abstract = "Theory and evidence suggest the potential value of prodromal intervention for infants at risk of developing autism. We report an initial case series (n = 8) of a parent-mediated, video-aided and interaction-focused intervention with infant siblings of autistic probands, beginning at 8-10 months of age. We outline the theory and evidence base behind this model and present data on feasibility, acceptability and measures ranging from parent-infant social interaction, to infant atypical behaviors, attention and cognition. The intervention proves to be both feasible and acceptable to families. Measurement across domains was successful and on larger samples promise to be an effective test of whether such an intervention in infancy will modify emergent atypical developmental trajectories in infants at risk for autism.",

author = "Jonathan Green and Wan, {Ming Wai} and Jeanne Guiraud and Samina Holsgrove and Janet McNally and Vicky Slonims and Mayada Elsabbagh and Tony Charman and Andrew Pickles and Mark Johnson and {The BASIS Team}",

year = "2013",

month = nov,

doi = "10.1007/s10803-013-1797-8",

language = "English",

volume = "43",

pages = "2502--2514",

journal = "Journal of Autism and Developmental Disorders",

publisher = "Springer",

number = "11",

}

TY - JOUR

T1 - Intervention for Infants at Risk of Developing Autism

T2 - A Case Series

AU - Green, Jonathan

AU - Wan, Ming Wai

AU - Guiraud, Jeanne

AU - Holsgrove, Samina

AU - McNally, Janet

AU - Slonims, Vicky

AU - Elsabbagh, Mayada

AU - Charman, Tony

AU - Pickles, Andrew

AU - Johnson, Mark

AU - The BASIS Team

PY - 2013/11

Y1 - 2013/11

N2 - Theory and evidence suggest the potential value of prodromal intervention for infants at risk of developing autism. We report an initial case series (n = 8) of a parent-mediated, video-aided and interaction-focused intervention with infant siblings of autistic probands, beginning at 8-10 months of age. We outline the theory and evidence base behind this model and present data on feasibility, acceptability and measures ranging from parent-infant social interaction, to infant atypical behaviors, attention and cognition. The intervention proves to be both feasible and acceptable to families. Measurement across domains was successful and on larger samples promise to be an effective test of whether such an intervention in infancy will modify emergent atypical developmental trajectories in infants at risk for autism.

AB - Theory and evidence suggest the potential value of prodromal intervention for infants at risk of developing autism. We report an initial case series (n = 8) of a parent-mediated, video-aided and interaction-focused intervention with infant siblings of autistic probands, beginning at 8-10 months of age. We outline the theory and evidence base behind this model and present data on feasibility, acceptability and measures ranging from parent-infant social interaction, to infant atypical behaviors, attention and cognition. The intervention proves to be both feasible and acceptable to families. Measurement across domains was successful and on larger samples promise to be an effective test of whether such an intervention in infancy will modify emergent atypical developmental trajectories in infants at risk for autism.

U2 - 10.1007/s10803-013-1797-8

DO - 10.1007/s10803-013-1797-8

M3 - Article

C2 - 23532347

VL - 43

SP - 2502

EP - 2514

JO - Journal of Autism and Developmental Disorders

JF - Journal of Autism and Developmental Disorders

IS - 11

ER -

Intervention for Infants at Risk of Developing Autism: A Case Series

Abstract

Access to Document

Fingerprint

Cite this