TY - JOUR
T1 - Intrahepatic Cholestasis of Pregnancy
AU - Ovadia, Caroline
AU - Williamson, Catherine
PY - 2016/2/10
Y1 - 2016/2/10
N2 - Abstract Intrahepatic cholestasis of pregnancy, also known as obstetric cholestasis, is a pruritic condition of pregnancy, characterized by an underlying elevation in circulating bile acids and liver derangement, and associated with adverse fetal outcomes, such as preterm labor and stillbirth. Limited understanding of the underlying pathophysiology and mechanisms involved in adverse outcomes has previously restricted treatment options and pregnancy management. Recent advances in these research fields provide tantalizing targets to improve the care of pregnant women affected by this condition.
AB - Abstract Intrahepatic cholestasis of pregnancy, also known as obstetric cholestasis, is a pruritic condition of pregnancy, characterized by an underlying elevation in circulating bile acids and liver derangement, and associated with adverse fetal outcomes, such as preterm labor and stillbirth. Limited understanding of the underlying pathophysiology and mechanisms involved in adverse outcomes has previously restricted treatment options and pregnancy management. Recent advances in these research fields provide tantalizing targets to improve the care of pregnant women affected by this condition.
U2 - 10.1016/j.clindermatol.2016.02.004
DO - 10.1016/j.clindermatol.2016.02.004
M3 - Article
SN - 0738-081X
SP - -
JO - Clinics in Dermatology
JF - Clinics in Dermatology
ER -