TY - JOUR
T1 - Introduction to Radiomics
AU - Mayerhoefer, Marius E.
AU - Materka, Andrzej
AU - Langs, Georg
AU - Häggström, Ida
AU - Szczypiński, Piotr
AU - Gibbs, Peter
AU - Cook, Gary
PY - 2020/4/1
Y1 - 2020/4/1
N2 - Radiomics is a rapidly evolving field of research concerned with the extraction of quantitative metrics-the so-called radiomic features-within medical images. Radiomic features capture tissue and lesion characteristics such as heterogeneity and shape and may, alone or in combination with demographic, histologic, genomic, or proteomic data, be used for clinical problem solving. The goal of this continuing education article is to provide an introduction to the field, covering the basic radiomics workflow: feature calculation and selection, dimensionality reduction, and data processing. Potential clinical applications in nuclear medicine that include PET radiomics-based prediction of treatment response and survival will be discussed. Current limitations of radiomics, such as sensitivity to acquisition parameter variations, and common pitfalls will also be covered.
AB - Radiomics is a rapidly evolving field of research concerned with the extraction of quantitative metrics-the so-called radiomic features-within medical images. Radiomic features capture tissue and lesion characteristics such as heterogeneity and shape and may, alone or in combination with demographic, histologic, genomic, or proteomic data, be used for clinical problem solving. The goal of this continuing education article is to provide an introduction to the field, covering the basic radiomics workflow: feature calculation and selection, dimensionality reduction, and data processing. Potential clinical applications in nuclear medicine that include PET radiomics-based prediction of treatment response and survival will be discussed. Current limitations of radiomics, such as sensitivity to acquisition parameter variations, and common pitfalls will also be covered.
KW - Artificial intelligence
KW - Machine learning
KW - PET
KW - Radiomics
KW - Single-photon emission tomography
UR - http://www.scopus.com/inward/record.url?scp=85082979497&partnerID=8YFLogxK
U2 - 10.2967/jnumed.118.222893
DO - 10.2967/jnumed.118.222893
M3 - Article
C2 - 32060219
SN - 1535-5667
VL - 61
SP - 488
EP - 495
JO - Journal of nuclear medicine : official publication, Society of Nuclear Medicine
JF - Journal of nuclear medicine : official publication, Society of Nuclear Medicine
IS - 4
ER -