Introduction to Radiomics

Marius E. Mayerhoefer, Andrzej Materka, Georg Langs, Ida Häggström, Piotr Szczypiński, Peter Gibbs, Gary Cook

Research output: Contribution to journalArticlepeer-review

807 Citations (Scopus)

Abstract

Radiomics is a rapidly evolving field of research concerned with the extraction of quantitative metrics-the so-called radiomic features-within medical images. Radiomic features capture tissue and lesion characteristics such as heterogeneity and shape and may, alone or in combination with demographic, histologic, genomic, or proteomic data, be used for clinical problem solving. The goal of this continuing education article is to provide an introduction to the field, covering the basic radiomics workflow: feature calculation and selection, dimensionality reduction, and data processing. Potential clinical applications in nuclear medicine that include PET radiomics-based prediction of treatment response and survival will be discussed. Current limitations of radiomics, such as sensitivity to acquisition parameter variations, and common pitfalls will also be covered.

Original languageEnglish
Pages (from-to)488-495
Number of pages8
JournalJournal of nuclear medicine : official publication, Society of Nuclear Medicine
Volume61
Issue number4
DOIs
Publication statusPublished - 1 Apr 2020

Keywords

  • Artificial intelligence
  • Machine learning
  • PET
  • Radiomics
  • Single-photon emission tomography

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