Investigating the familial basis of heightened risk-taking in adolescents with Conduct Disorder and their unaffected relatives

TY - JOUR

T1 - Investigating the familial basis of heightened risk-taking in adolescents with Conduct Disorder and their unaffected relatives

AU - Sully, Kate

AU - Sonuga-Barke, Edmund J.S.

AU - Savage, Justin

AU - Fairchild, Graeme

PY - 2016

Y1 - 2016

N2 - Previous studies have demonstrated increased risk-taking in adolescents with Conduct Disorder (CD) compared with typically developing controls. Increased risk-taking may partly mediate the pathway from genetic or environmental risk to CD. We investigated the familial basis of risk-taking by examining whether the unaffected relatives of CD probands (n = 22) showed heightened risk-taking in a gambling task, in common with affected probands (n = 44). Adolescents with CD were more likely to select risky options than the typically developing controls (n = 37) and unaffected relatives. Our findings confirm the association between CD and increased risk-taking, but suggest that this decision-making style may not have a familial basis.

AB - Previous studies have demonstrated increased risk-taking in adolescents with Conduct Disorder (CD) compared with typically developing controls. Increased risk-taking may partly mediate the pathway from genetic or environmental risk to CD. We investigated the familial basis of risk-taking by examining whether the unaffected relatives of CD probands (n = 22) showed heightened risk-taking in a gambling task, in common with affected probands (n = 44). Adolescents with CD were more likely to select risky options than the typically developing controls (n = 37) and unaffected relatives. Our findings confirm the association between CD and increased risk-taking, but suggest that this decision-making style may not have a familial basis.

U2 - 10.1080/87565641.2016.1145223

DO - 10.1080/87565641.2016.1145223

M3 - Article

SN - 8756-5641

VL - 41

SP - 93

EP - 106

JO - Developmental Neuropsychology

JF - Developmental Neuropsychology

IS - 1-2

ER -