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Is testicular macrocalcification a risk for malignancy? Tumor development on ultrasonographic follow-up of preexisting intratesticular macrocalcification

Research output: Contribution to journalArticlepeer-review

Malene R. Pedersen, Emily C. Bartlett, Christian Brown, Søren R. Rafaelsen, Maria E. Sellars, Paul S. Sidhu

Original languageEnglish
Pages (from-to)2949-2953
Number of pages5
JournalJournal of Ultrasound in Medicine
Issue number12
Early online date1 Dec 2018
Accepted/In press26 Mar 2018
E-pub ahead of print1 Dec 2018

King's Authors


Testicular macrocalcification is an uncommon finding when imaging the scrotum with ultrasonography (US). It is not normally a recognized risk factor for development of testicular malignancy, and patients are not usually offered follow-up US examinations or counseled for self-examination. This aspect is in distinction to patients with testicular microlithiasis (usually with an additional risk factor), who are offered follow-up on the assumption that microlithiasis is associated with malignancy. We report a series of 6 patients with predetermined testicular macrocalcification, with development of a malignancy on follow-up US. We encourage US follow-up examinations for patients with macrocalcification, potentially in a similar manner as for those with testicular microlithiasis.

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