Isolation of the avian homologue of the homeobox gene Mox2 and analysis of its expression pattern in developing somites and limbs

TY - JOUR

T1 - Isolation of the avian homologue of the homeobox gene Mox2 and analysis of its expression pattern in developing somites and limbs

AU - Rallis, C

AU - Stamataki, D

AU - Pontikakis, S

AU - Mankoo, B S

AU - Karagogeos, D

PY - 2001

Y1 - 2001

N2 - We have isolated the cDNA of avian Mox2 and analyzed its expression pattern during somitogenesis and limb bud formation. Mox2 plays an important role in limb muscle differentiation in the mouse. Mox2 is expressed in the somites of developing chick embryos and in presumptive migrating myoblasts from the dermomyotome to the limb buds. It is also expressed in the ventral and dorsal part of limb buds and is associated with non-proliferating myoblasts. Significant differences were observed in chick and mouse expression patterns, namely in the chick dermomyotome and limb.

AB - We have isolated the cDNA of avian Mox2 and analyzed its expression pattern during somitogenesis and limb bud formation. Mox2 plays an important role in limb muscle differentiation in the mouse. Mox2 is expressed in the somites of developing chick embryos and in presumptive migrating myoblasts from the dermomyotome to the limb buds. It is also expressed in the ventral and dorsal part of limb buds and is associated with non-proliferating myoblasts. Significant differences were observed in chick and mouse expression patterns, namely in the chick dermomyotome and limb.

U2 - 10.1016/S0925-4773(01)00354-9

DO - 10.1016/S0925-4773(01)00354-9

M3 - Article

VL - 104

SP - 121

EP - 124

JO - Mechanisms of Development

JF - Mechanisms of Development

IS - 1-2

ER -