Isothiocyanato-calix[4]phyrin-(1,1,1,1): A useful intermediate for the synthesis of derivatised anion sensors

Sushil C. Jha, Mark Lorch, Robert A. Lewis, Stephen J. Archibald*, Ross W. Boyle

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

24 Citations (Scopus)

Abstract

A calix[4]phyrin-(1,1,1,1) substituted with a 4-isothiocyanatophenyl group has been synthesised and used to attach the macrocycle to a solid support. The NCS group can also be used to further functionalise the calix[4]phyrin-(1,1,1,1) by reaction with amines and amino acids. Stability constants for anion binding by the calix[4]phyrin-(1,1,1,1) are reported and these show a clear ability to differentiate F- and HSO4- from Cl-, Br-, I- which can be detected by both NMR and UV-visible spectroscopy.

Original languageEnglish
Pages (from-to)1970-1974
Number of pages5
JournalORGANIC AND BIOMOLECULAR CHEMISTRY
Volume5
Issue number12
DOIs
Publication statusPublished - 2007

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