Jasmine absolute (Jasminum grandiflora L.) and its mode of action on guinea-pig ileum in vitro

M Lis-Balchin; S Hart; B W H Lo

doi:10.1002/ptr.935

Jasmine absolute (Jasminum grandiflora L.) and its mode of action on guinea-pig ileum in vitro

M Lis-Balchin, S Hart, B W H Lo

King's College London

Research output: Contribution to journal › Article › peer-review

24 Citations (Scopus)

Abstract

Jasmine (Jasminum grandiflorum L.) is used in aromatherapy as a holistic treatment for apathy, hysteria, uterine disorders and childbirth, muscle relaxation and coughs. Its stimulant nature, on inhalation, has been shown both in animals and man. Jasmine has a spasmolytic activity on guinea-pig ileum and rat uterus in vitro. The mechanism of action of the spasmolytic activity, studied in vitro using a guinea-pig ileum smooth muscle preparation, was postsynaptic and not atropine-like. The spasmolytic effect of jasmine absolute was most likely to be mediated through cAMP, and not through cGMP. The mode of action in vitro resembled that of geranium, lavender and peppermint oils. The contradictory effect in vitro and in vivo is probably due to the solely physiological effects of jasmine absolute in vitro (producing a relaxation) compared with that in vivo, where it has a strong psychological input, producing a stimulant effect in man and enhanced movement in animals. Copyright (C) 2002 John Wiley Sons, Ltd.

Original language	English
Pages (from-to)	437 - 439
Number of pages	3
Journal	PHYTOTHERAPY RESEARCH
Volume	16
Issue number	5
DOIs	https://doi.org/10.1002/ptr.935
Publication status	Published - Aug 2002

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1002/ptr.935

Cite this

@article{c1f2bcf5f8b9421e81ba6ae11445d024,

title = "Jasmine absolute (Jasminum grandiflora L.) and its mode of action on guinea-pig ileum in vitro",

abstract = "Jasmine (Jasminum grandiflorum L.) is used in aromatherapy as a holistic treatment for apathy, hysteria, uterine disorders and childbirth, muscle relaxation and coughs. Its stimulant nature, on inhalation, has been shown both in animals and man. Jasmine has a spasmolytic activity on guinea-pig ileum and rat uterus in vitro. The mechanism of action of the spasmolytic activity, studied in vitro using a guinea-pig ileum smooth muscle preparation, was postsynaptic and not atropine-like. The spasmolytic effect of jasmine absolute was most likely to be mediated through cAMP, and not through cGMP. The mode of action in vitro resembled that of geranium, lavender and peppermint oils. The contradictory effect in vitro and in vivo is probably due to the solely physiological effects of jasmine absolute in vitro (producing a relaxation) compared with that in vivo, where it has a strong psychological input, producing a stimulant effect in man and enhanced movement in animals. Copyright (C) 2002 John Wiley Sons, Ltd.",

author = "M Lis-Balchin and S Hart and Lo, {B W H}",

year = "2002",

month = aug,

doi = "10.1002/ptr.935",

language = "English",

volume = "16",

pages = "437 -- 439",

journal = "PHYTOTHERAPY RESEARCH",

publisher = "John Wiley and Sons Ltd",

number = "5",

}

TY - JOUR

T1 - Jasmine absolute (Jasminum grandiflora L.) and its mode of action on guinea-pig ileum in vitro

AU - Lis-Balchin, M

AU - Hart, S

AU - Lo, B W H

PY - 2002/8

Y1 - 2002/8

N2 - Jasmine (Jasminum grandiflorum L.) is used in aromatherapy as a holistic treatment for apathy, hysteria, uterine disorders and childbirth, muscle relaxation and coughs. Its stimulant nature, on inhalation, has been shown both in animals and man. Jasmine has a spasmolytic activity on guinea-pig ileum and rat uterus in vitro. The mechanism of action of the spasmolytic activity, studied in vitro using a guinea-pig ileum smooth muscle preparation, was postsynaptic and not atropine-like. The spasmolytic effect of jasmine absolute was most likely to be mediated through cAMP, and not through cGMP. The mode of action in vitro resembled that of geranium, lavender and peppermint oils. The contradictory effect in vitro and in vivo is probably due to the solely physiological effects of jasmine absolute in vitro (producing a relaxation) compared with that in vivo, where it has a strong psychological input, producing a stimulant effect in man and enhanced movement in animals. Copyright (C) 2002 John Wiley Sons, Ltd.

AB - Jasmine (Jasminum grandiflorum L.) is used in aromatherapy as a holistic treatment for apathy, hysteria, uterine disorders and childbirth, muscle relaxation and coughs. Its stimulant nature, on inhalation, has been shown both in animals and man. Jasmine has a spasmolytic activity on guinea-pig ileum and rat uterus in vitro. The mechanism of action of the spasmolytic activity, studied in vitro using a guinea-pig ileum smooth muscle preparation, was postsynaptic and not atropine-like. The spasmolytic effect of jasmine absolute was most likely to be mediated through cAMP, and not through cGMP. The mode of action in vitro resembled that of geranium, lavender and peppermint oils. The contradictory effect in vitro and in vivo is probably due to the solely physiological effects of jasmine absolute in vitro (producing a relaxation) compared with that in vivo, where it has a strong psychological input, producing a stimulant effect in man and enhanced movement in animals. Copyright (C) 2002 John Wiley Sons, Ltd.

UR - http://www.scopus.com/inward/record.url?scp=0036667472&partnerID=8YFLogxK

U2 - 10.1002/ptr.935

DO - 10.1002/ptr.935

M3 - Article

VL - 16

SP - 437

EP - 439

JO - PHYTOTHERAPY RESEARCH

JF - PHYTOTHERAPY RESEARCH

IS - 5

ER -

Jasmine absolute (Jasminum grandiflora L.) and its mode of action on guinea-pig ileum in vitro

Abstract

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this