Laboratory issues in the implementation of the marker method

TY - JOUR

T1 - Laboratory issues in the implementation of the marker method

AU - Cowan, David A.

AU - Bartlett, Christiaan

PY - 2009/8

Y1 - 2009/8

N2 - Two important biomarkers for the identification of growth hormone or IGF-I administration are IGF-I and P-III-P. These substances are determined in plasma or preferably in serum. There are a number of assays on the market for IGF-I but only two for P-III-P. The principles behind these assays and the choice of assays for doping control purposes are discussed. The future possibility of quantification by mass spectrometry is also briefly discussed. (C) 2009 Published by Elsevier Ltd.

AB - Two important biomarkers for the identification of growth hormone or IGF-I administration are IGF-I and P-III-P. These substances are determined in plasma or preferably in serum. There are a number of assays on the market for IGF-I but only two for P-III-P. The principles behind these assays and the choice of assays for doping control purposes are discussed. The future possibility of quantification by mass spectrometry is also briefly discussed. (C) 2009 Published by Elsevier Ltd.

U2 - 10.1016/j.ghir.2009.04.005

DO - 10.1016/j.ghir.2009.04.005

M3 - Article

VL - 19

SP - 357

EP - 360

JO - GROWTH HORMONE AND IGF RESEARCH

JF - GROWTH HORMONE AND IGF RESEARCH

IS - 4

ER -