King's College London

Research portal

Lactate production process

Research output: Patent

Andrew James Surman (Inventor), Stephen Alexander Calder Smith (Inventor)

Original languageEnglish
Publication statusPublished - 2014

King's Authors


A process for producing a compound of formula (I) is provided. The process comprises reacting a mixture comprising a compound of formula (IIA) and a compound of formula (IIB) with an alkyl alcohol in the presence of a Candida antarctica lipase B enzyme to produce a product comprising the compound of formula (I) and the compound of formula (IIB); wherein R1 is C1 to C6 alkyl; and wherein R2 is H or C1 to C12 alkyl. Also provided are processes for the production of R-lactic acid, oligomeric R-lactic acid, R,R-lactide, poly-R-lactic acid, alkyl S-lactate, S-lactic acid, oligomeric S-lactic acid, S,S-lactide, poly S-lactic acid and stereocomplex polylactic acid.

View graph of relations

© 2018 King's College London | Strand | London WC2R 2LS | England | United Kingdom | Tel +44 (0)20 7836 5454