Langerhans cell histiocytosis: a diagnostic dilemma

TY - JOUR

T1 - Langerhans cell histiocytosis

T2 - a diagnostic dilemma

AU - Ryan, Paul L

AU - Piper, Kim M

AU - Hughes, Francis J

PY - 2012/12

Y1 - 2012/12

N2 - Langerhans cell histiocytosis (LCH) is a rare clonal neoplastic disorder of unknown aetiology which can present with a diverse range of clinical presentations. It encompasses a diverse number of idiopathic conditions which can involve multiple body systems and is characterized by bone marrow-derived Langerhans cell proliferation. The disease can affect multiple body systems and lesions can be solitary or widespread. We present a case of a multifocal eosinophilic granuloma (LCH) in a young adult female with clinical signs and symptoms similar to aggressive periodontitis. Clinical Relevance: Langerhans cell histiocytosis is a rare disease which can have a similar clinical presentation to aggressive periodontitis.

AB - Langerhans cell histiocytosis (LCH) is a rare clonal neoplastic disorder of unknown aetiology which can present with a diverse range of clinical presentations. It encompasses a diverse number of idiopathic conditions which can involve multiple body systems and is characterized by bone marrow-derived Langerhans cell proliferation. The disease can affect multiple body systems and lesions can be solitary or widespread. We present a case of a multifocal eosinophilic granuloma (LCH) in a young adult female with clinical signs and symptoms similar to aggressive periodontitis. Clinical Relevance: Langerhans cell histiocytosis is a rare disease which can have a similar clinical presentation to aggressive periodontitis.

KW - Adult

KW - Aggressive Periodontitis

KW - Diagnosis, Differential

KW - Eosinophilic Granuloma

KW - Female

KW - Histiocytosis, Langerhans-Cell

KW - Humans

KW - Mandibular Neoplasms

M3 - Article

C2 - 23367637

SN - 0305-5000

VL - 39

SP - 716-8, 720

JO - Dental Update

JF - Dental Update

IS - 10

M1 - N/A

ER -