Abstract
Background: Late gadolinium enhancement (LGE) is a widely used cardiac magnetic resonance imaging (MRI) technique to diagnose a broad range of ischemic and non-ischemic cardiomyopathies. Since its development and validation against histology already more than two decades ago, the clinical utility of LGE and its span of applications have increased considerably. Methods: In this review we will present the basic concepts of LGE imaging and its diagnostic and prognostic value, elaborate on recent developments and emerging methods, and finally discuss future prospects. Results: Continuous developments in 3 D imaging methods, motion correction techniques, water/fat-separated imaging, dark-blood methods, and scar quantification improved the performance and further expanded the clinical utility of LGE imaging. Conclusion: LGE imaging is the current noninvasive reference standard for the assessment of myocardial viability. Improvements in spatial resolution, scar-to-blood contrast, and water/fat-separated imaging further strengthened its position. Key Points: LGE MRI is the reference standard for the noninvasive assessment of myocardial viability LGE MRI is used to diagnose a broad range of non-ischemic cardiomyopathies in everyday clinical practice. Improvements in spatial resolution and scar-to-blood contrast further strengthened its position Continuous developments improve its performance and further expand its clinical utility
| Original language | English |
|---|---|
| Pages (from-to) | 491-504 |
| Number of pages | 14 |
| Journal | RoFo Fortschritte auf dem Gebiet der Rontgenstrahlen und der Bildgebenden Verfahren |
| Volume | 194 |
| Issue number | 5 |
| Early online date | 23 Feb 2022 |
| DOIs | |
| Publication status | Published - 2022 |
Keywords
- cardiac
- heart
- MR imaging
- tissue characterization
