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Le diagnostic prénatal et le devenir des patients atteints de spina bifida

Research output: Contribution to journalArticle

P Gressens, P Collin, P Lebarbier, I Husson, G Penneçot, P Blot, C Bonnier, P Evrard, Pierre Gressens

Original languageFrench
Pages (from-to)1004-1008
Number of pages5
JournalArchives De Pediatrie
Issue number9
Publication statusPublished - Sep 1998

King's Authors


The frequency of new cases of myelomeningocele has largely decreased in the last 10 years in several countries of western Europe; the emergence of widespread prenatal diagnosis is probably one of the main reasons. However, the outcome of spina bifida which eludes the prenatal diagnosis, or in cases where termination was refused by parents, remains badly known. To our knowledge, there is no recent data on the outcome of children with spina bifida. Moreover, available data, depending on their European or American origin, indicate different functional outcomes. This led us to re-evaluate the mechanisms involved in the prenatal diagnosis of spina bifida and the outcome of our patients with spina bifida. The aim of this paper is to give a short description of the "rules and principles" of prenatal diagnosis as it is applied in our centres, as well as a brief overview of the outcome of 137 cases of spina bifida. In the retrospective study, three major aspects were evaluated: 1) frequency and types of surgeries and their benefits; 2) socio-psychological adaptation of the patients; 3) educational level and learning disabilities.

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