King's College London

Research portal

Left entorhinal cortex and object recognition

Research output: Contribution to journalArticle

Adele James, Tim J. von Oertzen, Ray Norbury, Hans-Juergen Huppertz, Karen R. Brandt

Original languageEnglish
Pages (from-to)363-367
Number of pages3
JournalNeuroreport
Volume29
Issue number5
DOIs
Publication statusPublished - 21 Mar 2018

Documents

King's Authors

Abstract

The present research explored the role of the medial temporal lobes in object memory in the unique patient MR, who has a selective lesion to her left lateral entorhinal cortex. Two experiments explored recognition memory for object identity and object location in MR and matched controls. The results showed that MR had intact performance in an object location task [MR=0.70, controls=0.69, t(6)=0.06, P>0.05], but was impaired in an object identity task [MR=0.62, controls=0.84, t(6)=-4.12, P<0.05]. No differences in correct recollection or familiarity emerged. These results suggest a differential role of the entorhinal cortex in object recognition memory. The current research is therefore the first patient study to show the role of the lateral entorhinal cortex in object identity recognition and suggests that current medial temporal lobe theoretical models on both object and recognition memory require a theoretical re-think to account for the contributions of the entorhinal cortex in these processes.

View graph of relations

© 2018 King's College London | Strand | London WC2R 2LS | England | United Kingdom | Tel +44 (0)20 7836 5454