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Les leucomalacies périventriculaires. I. Aspects histologiques et étiopathogéniques

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Les leucomalacies périventriculaires. I. Aspects histologiques et étiopathogéniques. / Marret, S; Zupan, V; Gressens, P; Lagercrantz, H; Evrard, P.

In: Archives De Pediatrie, Vol. 5, No. 5, 05.1998, p. 525-37.

Research output: Contribution to journalArticle

Harvard

Marret, S, Zupan, V, Gressens, P, Lagercrantz, H & Evrard, P 1998, 'Les leucomalacies périventriculaires. I. Aspects histologiques et étiopathogéniques', Archives De Pediatrie, vol. 5, no. 5, pp. 525-37.

APA

Marret, S., Zupan, V., Gressens, P., Lagercrantz, H., & Evrard, P. (1998). Les leucomalacies périventriculaires. I. Aspects histologiques et étiopathogéniques. Archives De Pediatrie, 5(5), 525-37.

Vancouver

Marret S, Zupan V, Gressens P, Lagercrantz H, Evrard P. Les leucomalacies périventriculaires. I. Aspects histologiques et étiopathogéniques. Archives De Pediatrie. 1998 May;5(5):525-37.

Author

Marret, S ; Zupan, V ; Gressens, P ; Lagercrantz, H ; Evrard, P. / Les leucomalacies périventriculaires. I. Aspects histologiques et étiopathogéniques. In: Archives De Pediatrie. 1998 ; Vol. 5, No. 5. pp. 525-37.

Bibtex Download

@article{ca15b9d098a14b6c8f3afebd2bddeeaa,
title = "Les leucomalacies p{\'e}riventriculaires. I. Aspects histologiques et {\'e}tiopathog{\'e}niques",
abstract = "The term 'periventricular leukomalacia' (PVL) usually covers necrotic and/or gliotic lesions from perinatal origin occurring in the periventricular ring of telencephalic white matter. PVLs are found post-mortem in one third of brains from autopsies of premature infants; PVLs are diagnosed in 4 to 10{\%} of infants born before 33 weeks of gestation and remaining alive more than 3 days after birth. PVL is very rare in at term infants. The proportion of PVLs from prenatal origin is estimated between one third and one half of cases. Recent progresses in neuroepidemiology, developmental neurobiology and imaging methods permit to revisit the pathophysiology of PVLs on a multifactorial basis. The final result of these multiple factors seem to be calcium influx due to glutamatergic overactivation triggered by cytokines, infection and inflammation, and deficit in neurotrophic factors. Periventricular topography can be explained by properties of intracerebral vascular wall at this stage of angiogenesis and by perfusion failure/hypoxia.",
keywords = "Humans, Infant, Newborn, Leukomalacia, Periventricular",
author = "S Marret and V Zupan and P Gressens and H Lagercrantz and P Evrard",
year = "1998",
month = "5",
language = "French",
volume = "5",
pages = "525--37",
journal = "Archives De Pediatrie",
issn = "0929-693X",
publisher = "Elsevier Masson",
number = "5",

}

RIS (suitable for import to EndNote) Download

TY - JOUR

T1 - Les leucomalacies périventriculaires. I. Aspects histologiques et étiopathogéniques

AU - Marret, S

AU - Zupan, V

AU - Gressens, P

AU - Lagercrantz, H

AU - Evrard, P

PY - 1998/5

Y1 - 1998/5

N2 - The term 'periventricular leukomalacia' (PVL) usually covers necrotic and/or gliotic lesions from perinatal origin occurring in the periventricular ring of telencephalic white matter. PVLs are found post-mortem in one third of brains from autopsies of premature infants; PVLs are diagnosed in 4 to 10% of infants born before 33 weeks of gestation and remaining alive more than 3 days after birth. PVL is very rare in at term infants. The proportion of PVLs from prenatal origin is estimated between one third and one half of cases. Recent progresses in neuroepidemiology, developmental neurobiology and imaging methods permit to revisit the pathophysiology of PVLs on a multifactorial basis. The final result of these multiple factors seem to be calcium influx due to glutamatergic overactivation triggered by cytokines, infection and inflammation, and deficit in neurotrophic factors. Periventricular topography can be explained by properties of intracerebral vascular wall at this stage of angiogenesis and by perfusion failure/hypoxia.

AB - The term 'periventricular leukomalacia' (PVL) usually covers necrotic and/or gliotic lesions from perinatal origin occurring in the periventricular ring of telencephalic white matter. PVLs are found post-mortem in one third of brains from autopsies of premature infants; PVLs are diagnosed in 4 to 10% of infants born before 33 weeks of gestation and remaining alive more than 3 days after birth. PVL is very rare in at term infants. The proportion of PVLs from prenatal origin is estimated between one third and one half of cases. Recent progresses in neuroepidemiology, developmental neurobiology and imaging methods permit to revisit the pathophysiology of PVLs on a multifactorial basis. The final result of these multiple factors seem to be calcium influx due to glutamatergic overactivation triggered by cytokines, infection and inflammation, and deficit in neurotrophic factors. Periventricular topography can be explained by properties of intracerebral vascular wall at this stage of angiogenesis and by perfusion failure/hypoxia.

KW - Humans

KW - Infant, Newborn

KW - Leukomalacia, Periventricular

M3 - Article

C2 - 9759188

VL - 5

SP - 525

EP - 537

JO - Archives De Pediatrie

JF - Archives De Pediatrie

SN - 0929-693X

IS - 5

ER -

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