Leveraging circulating microbial DNA for early cancer detection

Radhika Kataria; Saeed Shoaie; Anita Grigoriadis; Jonathan C.M. Wan

doi:10.1016/j.trecan.2023.08.001

Leveraging circulating microbial DNA for early cancer detection

Radhika Kataria, Saeed Shoaie, Anita Grigoriadis, Jonathan C.M. Wan^*

^*Corresponding author for this work

Research output: Contribution to journal › Short survey › peer-review

1 Citation (Scopus)

Abstract

Microbial cell-free DNA (microbial cfDNA) offers a minimally invasive approach for profiling the microbiome. Despite technical and biological challenges, the potential of microbial cfDNA for cancer detection is increasingly being evaluated using deep sequencing, novel laboratory approaches, and computational methods. Targeting the microbiome using liquid biopsies could improve early cancer detection.

Original language	English
Pages (from-to)	879-882
Number of pages	4
Journal	Trends in Cancer
Volume	9
Issue number	11
DOIs	https://doi.org/10.1016/j.trecan.2023.08.001
Publication status	Published - Nov 2023

Keywords

cancer
circulating microbial DNA
early detection
liquid biopsy
microbiome

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.trecan.2023.08.001

Cite this

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title = "Leveraging circulating microbial DNA for early cancer detection",

abstract = "Microbial cell-free DNA (microbial cfDNA) offers a minimally invasive approach for profiling the microbiome. Despite technical and biological challenges, the potential of microbial cfDNA for cancer detection is increasingly being evaluated using deep sequencing, novel laboratory approaches, and computational methods. Targeting the microbiome using liquid biopsies could improve early cancer detection.",

keywords = "cancer, circulating microbial DNA, early detection, liquid biopsy, microbiome",

author = "Radhika Kataria and Saeed Shoaie and Anita Grigoriadis and Wan, {Jonathan C.M.}",

note = "Publisher Copyright: {\textcopyright} 2023 The Author(s)",

year = "2023",

month = nov,

doi = "10.1016/j.trecan.2023.08.001",

language = "English",

volume = "9",

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journal = "Trends in Cancer",

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TY - JOUR

T1 - Leveraging circulating microbial DNA for early cancer detection

AU - Kataria, Radhika

AU - Shoaie, Saeed

AU - Grigoriadis, Anita

AU - Wan, Jonathan C.M.

PY - 2023/11

Y1 - 2023/11

N2 - Microbial cell-free DNA (microbial cfDNA) offers a minimally invasive approach for profiling the microbiome. Despite technical and biological challenges, the potential of microbial cfDNA for cancer detection is increasingly being evaluated using deep sequencing, novel laboratory approaches, and computational methods. Targeting the microbiome using liquid biopsies could improve early cancer detection.

AB - Microbial cell-free DNA (microbial cfDNA) offers a minimally invasive approach for profiling the microbiome. Despite technical and biological challenges, the potential of microbial cfDNA for cancer detection is increasingly being evaluated using deep sequencing, novel laboratory approaches, and computational methods. Targeting the microbiome using liquid biopsies could improve early cancer detection.

KW - cancer

KW - circulating microbial DNA

KW - early detection

KW - liquid biopsy

KW - microbiome

UR - http://www.scopus.com/inward/record.url?scp=85169507400&partnerID=8YFLogxK

U2 - 10.1016/j.trecan.2023.08.001

DO - 10.1016/j.trecan.2023.08.001

M3 - Short survey

C2 - 37659908

AN - SCOPUS:85169507400

SN - 2405-8033

VL - 9

SP - 879

EP - 882

JO - Trends in Cancer

JF - Trends in Cancer

IS - 11

ER -

Leveraging circulating microbial DNA for early cancer detection

Abstract

Keywords

UN SDGs

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