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LINTENOLIDES, NEW PENTACYCLIC BIOACTIVE SESTERTERPENES FROM THE CARIBBEAN SPONGE CACOSPONGIA CF LINTEIFORMIS

Research output: Contribution to journalArticle

M R CONTE, E FATTORUSSO, V LANZOTTI, S MAGNO, L MAYOL

Original languageEnglish
Pages (from-to)849-856
Number of pages8
JournalTETRAHEDRON
Volume50
Issue number3
DOIs
Publication statusPublished - 17 Jan 1994

King's Authors

Abstract

New pentacyclic sesterterpenes, lintenolide A (2 a, b) and lintenolide B (3 a, b), have been characterized from the caribbean sponge Cacospongia cf. linteiformis. The structure elucidation of these compounds was accomplished by using 2D NMR experiments, including H-1-H-1 (COSY), H-1-C-13 (HETCORR and COLOC) and rotating frame NOE (ROESY). Compounds showed high ichthyotoxicity and antifeedant activity, which suggest their potential role as natural feeding deterrents.

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