Lipoma Arborescens Successfully Treated With 90Y Synovectomy

TY - JOUR

T1 - Lipoma Arborescens Successfully Treated With 90Y Synovectomy

AU - O'Doherty, James

AU - Clauss, Ralf

AU - Scuffham, James

AU - Khan, Aman

PY - 2014/2

Y1 - 2014/2

N2 - Lipoma arborescens (LA) in the knee is a benign intra-articular lipomatous proliferation of the synovial membrane, and data on treatment of LA by radionuclide therapy is sparse. We present a rare case of bilateral LA in the knees successfully treated with injection of 90Y-citrate colloid. We assessed the biodistribution of the radiopharmaceutical through the use of SPECT/CT imaging. Our images show slight redistribution of the radiocolloid in the knee joint, whereas most of the radioactivity remains localized around the LA. MRI scans confirmed the efficacy of this treatment, with a significant reduction in LA volume after 6 months.

AB - Lipoma arborescens (LA) in the knee is a benign intra-articular lipomatous proliferation of the synovial membrane, and data on treatment of LA by radionuclide therapy is sparse. We present a rare case of bilateral LA in the knees successfully treated with injection of 90Y-citrate colloid. We assessed the biodistribution of the radiopharmaceutical through the use of SPECT/CT imaging. Our images show slight redistribution of the radiocolloid in the knee joint, whereas most of the radioactivity remains localized around the LA. MRI scans confirmed the efficacy of this treatment, with a significant reduction in LA volume after 6 months.

U2 - 10.1097/RLU.0000000000000317

DO - 10.1097/RLU.0000000000000317

M3 - Article

SN - 0363-9762

VL - 39

SP - 187

EP - 189

JO - Clinical Nuclear Medicine

JF - Clinical Nuclear Medicine

IS - 2

ER -