Long term sequelae of bronchopulmonary dysplasia: Long term sequelae of BPD

TY - CHAP

T1 - Long term sequelae of bronchopulmonary dysplasia

T2 - Long term sequelae of BPD

AU - Dassios, Theodore

AU - Greenough, Anne

PY - 2021

Y1 - 2021

N2 - Bronchopulmonary dysplasia (BPD) is now the commonest adverse outcome of very premature birth; this is largely due to the increased survival of affected infants and the routine use of antenatal corticosteroids and postnatal surfactant. Unfortunately, individuals who have had BPD can suffer chronic respiratory morbidity including prolonged supplementary oxygen dependency, rehospitalisations due to respiratory problems in the first two years after birth and troublesome respiratory symptoms and lung function abnormalities even into adult hood. “BPD” children and adults also have a higher incidence of severe neurological problems such as cerebral palsy and delayed neurodevelopment compared to either healthy term born adults or prematurely born infants without BPD. Studies have demonstrated that their lung function may deteriorate prematurely, that is before puberty, putting them at risk of the early development of chronic obstructive pulmonary disease. Affected individuals require long term pulmonary follow-up and the complex and diverse clinical needs of these children and adults mandate coordinated interdisciplinary care.

AB - Bronchopulmonary dysplasia (BPD) is now the commonest adverse outcome of very premature birth; this is largely due to the increased survival of affected infants and the routine use of antenatal corticosteroids and postnatal surfactant. Unfortunately, individuals who have had BPD can suffer chronic respiratory morbidity including prolonged supplementary oxygen dependency, rehospitalisations due to respiratory problems in the first two years after birth and troublesome respiratory symptoms and lung function abnormalities even into adult hood. “BPD” children and adults also have a higher incidence of severe neurological problems such as cerebral palsy and delayed neurodevelopment compared to either healthy term born adults or prematurely born infants without BPD. Studies have demonstrated that their lung function may deteriorate prematurely, that is before puberty, putting them at risk of the early development of chronic obstructive pulmonary disease. Affected individuals require long term pulmonary follow-up and the complex and diverse clinical needs of these children and adults mandate coordinated interdisciplinary care.

M3 - Chapter

BT - European Respiratory Society Monograph

ER -