King's College London

PROOF-OF-PRINCIPLE EVALUATION OF IMMUNOMODULATORY DRUGS IN PROMOTING PHAGOCYTOSIS CAPACITY IN PATIENTS WITH LIVER FAILURE.

Bernsmeier, C., Tidswell, R., Ghataore, L., Patel, V. C., Singanayagam, A., Triantafyllou, E., Khamri, W., Heneghan, M., Willars, C., Bernal, W., Auzinger, G., Taylor, D. R., Vincent, R., Ma, Y., Thursz, M. R., Wendon, J. & Antoniades, C., 2015, In: Journal of Hepatology. 62, p. S324 1 p., P1294.

Research output: Contribution to journal › Meeting abstract › peer-review

Patients With Acute-on-Chronic Liver Failure Have Increased Numbers of Regulatory Immune Cells Expressing the Receptor Tyrosine Kinase MERTK

Bernsmeier, C., Pop, O. T., Singanayagam, A., Triantafyllou, E., Patel, V. C., Weston, C. J., Curbishley, S., Sadiq, F., Vergis, N., Khamri, W., Bernal, W., Auzinger, G., Heneghan, M., Ma, Y., Jassem, W., Heaton, N. D., Adams, D. H., Quaglia, A., Thursz, M. R., Wendon, J., & 1 othersAntoniades, C. G., Mar 2015, In: Gastroenterology. 148, 3, p. 603-615.e14 27 p.

Research output: Contribution to journal › Article › peer-review

Dysregulation of the Lysophosphatidylcholine/Autotaxin/Lysophosphatidic Acid Axis in Acute-on-Chronic Liver Failure Is Associated With Mortality and Systemic Inflammation by Lysophosphatidic Acid–Dependent Monocyte Activation

Trovato, F. M., Zia, R., Napoli, S., Wolfer, K., Huang, X., Morgan, P. E., Husbyn, H., Elgosbi, M., Lucangeli, M., Miquel, R., Wilson, I., Heaton, N. D., Heneghan, M. A., Auzinger, G., Antoniades, C. G., Wendon, J. A., Patel, V. C., Coen, M., Triantafyllou, E. & McPhail, M. J., Aug 2021, In: Hepatology. 74, 2, p. 907-925 19 p.

Research output: Contribution to journal › Article › peer-review

Immunometabolic profiling of ascites from patients with acute-on-chronic liver failure reveals increased MerTK plus immunosuppressive myeloid cells and cell death markers with preferential lipid metabolism compared to cirrhosis without organ failure

Singanayagam, A., Erminelli, D., Triantafyllou, E., Bernsmeier, C., Tunc, E., Krasniqi, M., Patel, V., Lebosse, F., Nathwani, R., Atkinson, A., Dhar, A., Heneghan, M., Auzinger, G., Khamri, W., Adams, D., Wendon, J., Thursz, M., McPhail, M. J. W. & Antoniades, H., Apr 2019, In: Journal of Hepatology. 70, p. E183-E183

Research output: Contribution to journal › Meeting Abstract › peer-review

MerTK expressing hepatic macrophages promote the resolution of inflammation in acute liver failure

Triantafyllou, E., Pop, O. T., Possamai, L. A., Wilhelm, A., Liaskou, E., Singanayagam, A., Bernsmeier, C., Khamri, W., Petts, G., Dargue, R., Davies, S. P., Tickle, J., Yuksel, M., Patel, V. C., Abeles, R. D., Stamataki, Z., Curbishley, S. M., Ma, Y., Wilson, I. D., Coen, M., & 7 othersWoollard, K. J., Quaglia, A., Wendon, J., Thursz, M. R., Adams, D. H., Weston, C. J. & Antoniades, C. G., Feb 2018, In: Gut. 67, 2, p. 333-347 15 p.

Research output: Contribution to journal › Article › peer-review

The efficacy of GLP-1RAs for the management of postprandial hypoglycemia following bariatric surgery: a systematic review

Llewelyn, D., Ellis, H., Aylwin, S., Ostarijas, E., Green, S., Sheridan, W., Chew, N. WS., le Roux, C. W., Miras, A. D., Patel, A. G., Vincent, R. & Dimitriadis, G. K., Jan 2023, In: Obesity. 31, 1, p. 20-30 11 p.

Research output: Contribution to journal › Review article › peer-review

Systematic review and meta-analysis of the diagnostic accuracy of procalcitonin for post-operative sepsis/infection in liver transplantation

Jerome, E., Cavazza, A., Menon, K. & McPhail, M. J., Oct 2022, In: Transplant Immunology. 74, 101675.

Research output: Contribution to journal › Article › peer-review

Plasma exchange in the intensive care unit: a narrative review

the Nine-I Investigators, Oct 2022, In: Intensive Care Medicine. 48, 10, p. 1382-1396 15 p.

Research output: Contribution to journal › Review article › peer-review

Hepatic arterial infusion chemotherapy versus transarterial chemoembolization for unresectable hepatocellular carcinoma: A systematic review with meta-analysis

Si, T., Huang, Z., Khorsandi, S. E., Ma, Y. & Heaton, N., 27 Sep 2022, In: Frontiers in Bioengineering and Biotechnology. 10, p. 1010824 1010824.

Research output: Contribution to journal › Article › peer-review

General Practitioner perspectives on factors that influence implementation of secondary care-initiated treatment in primary care: exploring implementation beyond the context of a clinical trial

Le Boutillier, C., Ahmed, H., Patel, V., McPhail, M., Carter, B., Ward, C. & Lawrence, V., 22 Sep 2022, (Accepted/In press) In: PLoS One.

Research output: Contribution to journal › Article › peer-review

Low dose interleukin-2 selectively expands circulating regulatory T cells but fails to promote liver allograft tolerance in humans

Lim, T. Y., Perpiñán, E., Londoño, M., Miquel, R., Ruiz, P., Kurt, A. S., Kodela, E., Cross, A. R., Berlin, C., Hester, J., Issa, F., Douiri, A., Volmer, F. H., Taubert, R., Williams, E., Demetris, A. J., Andrew, L., Gilbert, B., Lozano, J. J., Martinez-llordella, M., & 2 othersTree, T. & Sánchez-fueyo, A., Jan 2023, In: Journal of Hepatology. 78, 1, p. 153-164 12 p.

Research output: Contribution to journal › Article › peer-review

Low dose interleukin-2 selectively expands circulating regulatory T cells but fails to promote transplantation tolerance in humans

Lim, T. Y., Perpinan, E., Carlota Londono, M., Miquel, R., Ruiz, P., Kurt, A., Codela, E., Cross, A., Berlin, C., Hester, J., Issa, F., Douiri, A., Volmer, F., Taubert, R., Williams, E., Demetris, J., Lesniak, A., Bensimon, G., Lozano, J., Martinez-Llordella, M., & 2 othersTree, T. & Sanchez-Fueyo, A., Jul 2022, In: Journal of Hepatology. 77, p. S809-S809

Research output: Contribution to journal › Meeting Abstract › peer-review

Andrographolide can potentially rescue unusable liver grafts by reducing fat content, enhancing mitochondrial function, and inhibiting Th1/Th17 immunity

Huang, Z., Si, T., Huang, X., Anand, H., Filippi, C., Mitry, R., Dhawan, A., Jassem, W., Wang, Z., Heaton, N., Ji, L. & Ma, Y., Jul 2022, In: Journal of Hepatology. 77, p. S818-S820

Research output: Contribution to journal › Meeting Abstract › peer-review

Plasma ammonia levels predict hospitalisation with liver-related complications and mortality in clinically stable outpatients with cirrhosis

Tranah, T., Ballester, M-P., Carbonell-Asins, J. A., Ampuero, J., Alexandrino, G., Caracostea, A., Sanchez-Torrijos, Y., Thomsen, K., Kerbert, A., Capilla-Lozano, M., Romero-Gomez, M., Escudero-Garcia, D., Montoliu, C., Jalan, R. & Shawcross, D., 28 Jun 2022, (Accepted/In press) In: Journal of Hepatology.

Research output: Contribution to journal › Article › peer-review

Rifaximin reduces gut-derived inflammation and mucin degradation in cirrhosis and encephalopathy: RIFSYS randomised controlled trial

Patel, V. C., Lee, S., McPhail, M. J. W., Zamalloa, A., Witherden, E., Stoy, S., Vijay, G. M., Huang, X., Gencer, S., Coen, M., Tranah, T., Wendon, J., Bruce, K., Ehrlich, D., Edwards, L. A., Shoaie, S. & Shawcross, D. L., Feb 2022, In: Journal of Hepatology. 76, 2, p. 332-342 11 p.

Research output: Contribution to journal › Article › peer-review