Abstract
Moderate anticoagulation after mechanical heart valve replacement has been proposed to reduce the risk of bleeding related to lifelong anticoagulation. However, the efficacy of such reduced antithrombotic regimens is still unknown. The present prospective open-label, single-center, randomized controlled trial aimed to evaluate the safety and feasibility of reduced oral anticoagulation after isolated mechanical aortic valve replacement.
Original language | English |
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Pages (from-to) | 171-8 |
Number of pages | 8 |
Journal | American Heart Journal |
Volume | 160 |
Issue number | 1 |
DOIs | |
Publication status | Published - Jul 2010 |
Keywords
- Administration, Oral
- Young Adult
- Anticoagulants
- Dose-Response Relationship, Drug
- Humans
- Prognosis
- Postoperative Hemorrhage
- Thrombosis
- Italy
- Prospective Studies
- Risk Factors
- Adult
- Heart Valve Prosthesis
- Prosthesis Design
- Incidence
- Follow-Up Studies
- Middle Aged
- Aortic Valve Stenosis
- Female
- Male