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Magnetic resonance imaging of Meniere's disease: early clinical experience in a UK centre

Research output: Contribution to journalArticlepeer-review

Irumee Pai, S Mendis, Louisa Murdin, Philip Touska, Steve Connor

Original languageEnglish
Pages (from-to)302-310
JournalJournal of Laryngology and Otology
Volume134
Issue number4
Early online date3 Apr 2020
DOIs
E-pub ahead of print3 Apr 2020
Published2020

King's Authors

Abstract

Background
Recent developments in magnetic resonance imaging have enabled demonstration of endolymphatic hydrops, and the clinical application of these imaging studies in Ménière's disease is being explored.

Objective
To evaluate our centre's experience to date of hydrops magnetic resonance imaging in patients with episodic vertigo.

Methods
Magnetic resonance imaging was performed using a high-resolution three-dimensional fluid-attenuated inversion recovery sequence on a 3 Tesla scanner at 4 hours following double-dose gadolinium administration.

Results
The study included 31 patients, 28 of whom had a clinical diagnosis of Ménière's disease. In unilateral Ménière's disease, magnetic resonance imaging was able to lateralise endolymphatic hydrops to the clinically symptomatic ear in all cases. Mild hydrops was often seen in clinically asymptomatic ears.

Conclusion
There is a good correlation between the clinical symptoms and lateralisation of hydropic changes on magnetic resonance imaging. Further refinements of imaging techniques and grading system will likely improve the diagnostic accuracy and clinical utilisation of hydrops magnetic resonance imaging.

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