Make lithium great again - Precisely!

TY - JOUR

T1 - Make lithium great again - Precisely!

AU - “R-LiNK Consortium”

AU - Bellivier, Frank

AU - Young, Allan H

AU - Scott, Jan

AU - Etain, Bruno

AU - Cousins, David A

N1 - This article is protected by copyright. All rights reserved.

PY - 2020/10/23

Y1 - 2020/10/23

N2 - In their editorial "Make lithium great again!" Malhi and collaborators1 reviewed the common misconceptions surrounding tolerability and ease of administration, and the clinical phenotypes to consider when prescribing lithium for bipolar disorders (BD). Despite clinical practice guidelines recommending lithium as a first-line option in BD, its use appears to be declining. For example, in a recent analysis of prescribing practices in the USA between 1997 and 2016, lithium use in outpatients with BD declined from 30% to 18%.2 Given its established efficacy, this is of serious concern. Perhaps the strongest argument promulgated by those who do not prescribe lithium is that only a third of individuals with BD have an excellent prophylactic response.

AB - In their editorial "Make lithium great again!" Malhi and collaborators1 reviewed the common misconceptions surrounding tolerability and ease of administration, and the clinical phenotypes to consider when prescribing lithium for bipolar disorders (BD). Despite clinical practice guidelines recommending lithium as a first-line option in BD, its use appears to be declining. For example, in a recent analysis of prescribing practices in the USA between 1997 and 2016, lithium use in outpatients with BD declined from 30% to 18%.2 Given its established efficacy, this is of serious concern. Perhaps the strongest argument promulgated by those who do not prescribe lithium is that only a third of individuals with BD have an excellent prophylactic response.

UR - http://www.scopus.com/inward/record.url?scp=85096788819&partnerID=8YFLogxK

U2 - 10.1111/bdi.13023

DO - 10.1111/bdi.13023

M3 - Comment/debate

C2 - 33098168

SN - 1398-5647

JO - Bipolar Disorders

JF - Bipolar Disorders

ER -