Management of Patients With Severe Mitral Annular Calcification: JACC State-of-the-Art Review

Omar Chehab, Ross Roberts-Thomson, Antonio Bivona, Harminder Gill, Tiffany Patterson, Amit Pursnani, Karine Grigoryan, Bernardo Vargas, Ujala Bokhary, Christopher Blauth, Gianluca Lucchese, Vinayak Bapat, Mayra Guerrero, Simon Redwood, Bernard Prendergast*, Ronak Rajani

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

13 Citations (Scopus)


Mitral annular calcification (MAC) is a common and challenging pathologic condition, especially in the context of an aging society. Surgical mitral valve intervention in patients with MAC is difficult, with varying approaches to the calcified annular anatomy, and the advent of transcatheter valve interventions has provided additional treatment options. Advanced imaging provides the foundation for heart team discussions and management decisions concerning individual patients. This review focuses on the prognosis of, preoperative planning for, and management strategies for patients with MAC.

Original languageEnglish
Pages (from-to)722-738
Number of pages17
JournalJournal of the American College of Cardiology
Issue number7
Publication statusPublished - 16 Aug 2022


  • mitral annular calcification
  • mitral valve
  • surgery
  • valve-in-MAC


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