Managing respiratory complications in infants and newborns with congenital diaphragmatic hernia

Sandeep Shetty; Fahad M.S. Arattu Thodika; Anne Greenough

doi:10.1080/21678707.2020.1865915

Managing respiratory complications in infants and newborns with congenital diaphragmatic hernia

Sandeep Shetty, Fahad M.S. Arattu Thodika, Anne Greenough^*

^*Corresponding author for this work

Women & Children's Health

Research output: Contribution to journal › Review article › peer-review

1 Citation (Scopus)

Abstract

Introduction: Congenital diaphragmatic hernia (CDH) is one of the most challenging neonatal surgical conditions due to its high mortality and morbidity. A multidisciplinary approach is required regarding the management of affected infants, before birth, during their initial hospitalization and in their long-term follow-up. Areas covered: This review discusses the monitoring and management strategies for infants with CDH including during the prenatal and postnatal periods. It emphasizes the long-term sequelae these patients can suffer throughout childhood and adulthood. This article highlights the progress that has been made and where future developments have the potential to improve the outcome of this vulnerable patient population. A literature search was performed using Google Scholar, Science Direct and PubMed. Expert opinion: Advances in antenatal and neonatal care have improved the early survival of infants with CDH, but many infants are surviving with long-term morbidity. An increasing number of CDH survivors are now reaching adolescence and adulthood. New challenges arise regarding the prevention and management of their long-term problems.

Original language	English
Pages (from-to)	525-537
Number of pages	13
Journal	Expert opinion on orphan drugs
Volume	8
Issue number	12
DOIs	https://doi.org/10.1080/21678707.2020.1865915
Publication status	Published - 2020

Keywords

Congenital diaphragmatic hernia
gastro-esophageal reflux
long-term outcomes
pulmonary hypertension
respiratory complications

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1080/21678707.2020.1865915

Cite this

@article{001415a9d87b4aa1980f64e7595795de,

title = "Managing respiratory complications in infants and newborns with congenital diaphragmatic hernia",

abstract = "Introduction: Congenital diaphragmatic hernia (CDH) is one of the most challenging neonatal surgical conditions due to its high mortality and morbidity. A multidisciplinary approach is required regarding the management of affected infants, before birth, during their initial hospitalization and in their long-term follow-up. Areas covered: This review discusses the monitoring and management strategies for infants with CDH including during the prenatal and postnatal periods. It emphasizes the long-term sequelae these patients can suffer throughout childhood and adulthood. This article highlights the progress that has been made and where future developments have the potential to improve the outcome of this vulnerable patient population. A literature search was performed using Google Scholar, Science Direct and PubMed. Expert opinion: Advances in antenatal and neonatal care have improved the early survival of infants with CDH, but many infants are surviving with long-term morbidity. An increasing number of CDH survivors are now reaching adolescence and adulthood. New challenges arise regarding the prevention and management of their long-term problems.",

keywords = "Congenital diaphragmatic hernia, gastro-esophageal reflux, long-term outcomes, pulmonary hypertension, respiratory complications",

author = "Sandeep Shetty and {Arattu Thodika}, {Fahad M.S.} and Anne Greenough",

year = "2020",

doi = "10.1080/21678707.2020.1865915",

language = "English",

volume = "8",

pages = "525--537",

journal = "Expert opinion on orphan drugs",

issn = "2167-8707",

publisher = "Taylor and Francis Ltd.",

number = "12",

}

TY - JOUR

T1 - Managing respiratory complications in infants and newborns with congenital diaphragmatic hernia

AU - Shetty, Sandeep

AU - Arattu Thodika, Fahad M.S.

AU - Greenough, Anne

PY - 2020

Y1 - 2020

N2 - Introduction: Congenital diaphragmatic hernia (CDH) is one of the most challenging neonatal surgical conditions due to its high mortality and morbidity. A multidisciplinary approach is required regarding the management of affected infants, before birth, during their initial hospitalization and in their long-term follow-up. Areas covered: This review discusses the monitoring and management strategies for infants with CDH including during the prenatal and postnatal periods. It emphasizes the long-term sequelae these patients can suffer throughout childhood and adulthood. This article highlights the progress that has been made and where future developments have the potential to improve the outcome of this vulnerable patient population. A literature search was performed using Google Scholar, Science Direct and PubMed. Expert opinion: Advances in antenatal and neonatal care have improved the early survival of infants with CDH, but many infants are surviving with long-term morbidity. An increasing number of CDH survivors are now reaching adolescence and adulthood. New challenges arise regarding the prevention and management of their long-term problems.

AB - Introduction: Congenital diaphragmatic hernia (CDH) is one of the most challenging neonatal surgical conditions due to its high mortality and morbidity. A multidisciplinary approach is required regarding the management of affected infants, before birth, during their initial hospitalization and in their long-term follow-up. Areas covered: This review discusses the monitoring and management strategies for infants with CDH including during the prenatal and postnatal periods. It emphasizes the long-term sequelae these patients can suffer throughout childhood and adulthood. This article highlights the progress that has been made and where future developments have the potential to improve the outcome of this vulnerable patient population. A literature search was performed using Google Scholar, Science Direct and PubMed. Expert opinion: Advances in antenatal and neonatal care have improved the early survival of infants with CDH, but many infants are surviving with long-term morbidity. An increasing number of CDH survivors are now reaching adolescence and adulthood. New challenges arise regarding the prevention and management of their long-term problems.

KW - Congenital diaphragmatic hernia

KW - gastro-esophageal reflux

KW - long-term outcomes

KW - pulmonary hypertension

KW - respiratory complications

UR - http://www.scopus.com/inward/record.url?scp=85098633847&partnerID=8YFLogxK

U2 - 10.1080/21678707.2020.1865915

DO - 10.1080/21678707.2020.1865915

M3 - Review article

AN - SCOPUS:85098633847

SN - 2167-8707

VL - 8

SP - 525

EP - 537

JO - Expert opinion on orphan drugs

JF - Expert opinion on orphan drugs

IS - 12

ER -

Managing respiratory complications in infants and newborns with congenital diaphragmatic hernia

Abstract

Keywords

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this