Masseter function and skeletal malocclusion

J. J. Sciote*, G. Raoul, J. Ferri, J. Close, M. J. Horton, A. Rowlerson

*Corresponding author for this work

Research output: Contribution to journalLiterature reviewpeer-review

22 Citations (Scopus)

Abstract

The aim of this work is to review the relationship between the function of the masseter muscle and the occurrence of malocclusions. An analysis was made of the masseter muscle samples from subjects who underwent mandibular osteotomies. The size and proportion of type-II fibers (fast) decreases as facial height increases. Patients with mandibular asymmetry have more type-II fibers on the side of their deviation. The insulin-like growth factor and myostatin are expressed differently depending on the sex and fiber diameter. These differences in the distribution of fiber types and gene expression of this growth factor may be involved in long-term postoperative stability and require additional investigations. Muscle strength and bone length are two genetically determined factors in facial growth. Myosin 1H (MYOH1) is associated with prognathia in Caucasians. As future objectives, we propose to characterize genetic variations using "Genome Wide Association Studies" data and their relationships with malocclusions. (c) 2013 Elsevier Masson SAS. All rights reserved.

Original languageEnglish
Pages (from-to)79-85
Number of pages7
JournalRevue De Stomatologie et De Chirurgie Maxillo-Faciale
Volume114
Issue number2
DOIs
Publication statusPublished - Apr 2013

Keywords

  • Masseter muscle
  • Humans
  • Phenotype
  • Genotype
  • Malocclusion
  • ORTHOGNATHIC SURGERY
  • MASTICATORY MUSCLE
  • GENETIC-VARIATION
  • MORPHOLOGY
  • ISOFORMS
  • FIBERS
  • GROWTH
  • MICE
  • RAT

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