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Material Specificity Drives Medial Temporal Lobe Familiarity But Not Hippocampal Recollection

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Material Specificity Drives Medial Temporal Lobe Familiarity But Not Hippocampal Recollection. / Kafkas, Alex; Migo, Ellen M.; Morris, Robin G.; Kopelman, Michael D.; Montaldi, Daniela; Mayes, Andrew R.

In: Hippocampus, Vol. 27, No. 2, 01.02.2017, p. 194-209.

Research output: Contribution to journalArticle

Harvard

Kafkas, A, Migo, EM, Morris, RG, Kopelman, MD, Montaldi, D & Mayes, AR 2017, 'Material Specificity Drives Medial Temporal Lobe Familiarity But Not Hippocampal Recollection', Hippocampus, vol. 27, no. 2, pp. 194-209. https://doi.org/10.1002/hipo.22683

APA

Kafkas, A., Migo, E. M., Morris, R. G., Kopelman, M. D., Montaldi, D., & Mayes, A. R. (2017). Material Specificity Drives Medial Temporal Lobe Familiarity But Not Hippocampal Recollection. Hippocampus, 27(2), 194-209. https://doi.org/10.1002/hipo.22683

Vancouver

Kafkas A, Migo EM, Morris RG, Kopelman MD, Montaldi D, Mayes AR. Material Specificity Drives Medial Temporal Lobe Familiarity But Not Hippocampal Recollection. Hippocampus. 2017 Feb 1;27(2):194-209. https://doi.org/10.1002/hipo.22683

Author

Kafkas, Alex ; Migo, Ellen M. ; Morris, Robin G. ; Kopelman, Michael D. ; Montaldi, Daniela ; Mayes, Andrew R. / Material Specificity Drives Medial Temporal Lobe Familiarity But Not Hippocampal Recollection. In: Hippocampus. 2017 ; Vol. 27, No. 2. pp. 194-209.

Bibtex Download

@article{0d92bac5faca40b4b4bb48f03162fd23,
title = "Material Specificity Drives Medial Temporal Lobe Familiarity But Not Hippocampal Recollection",
abstract = "The specific role of the perirhinal (PRC), entorhinal (ERC) and parahippocampal cortices (PHC) in supporting familiarity-based recognition remains unknown. An fMRI study explored whether these medial temporal lobe (MTL) structures responded in the same way or differentially to familiarity as a function of stimulus type at recognition. A secondary aim was to explore whether the hippocampus responds in the same way to equally strong familiarity and recollection and whether this is influenced by the kind of stimulus involved. Univariate and multivariate analyses revealed that familiarity responses in the PRC, ERC, PHC and the amygdala are material-specific. Specifically, the PRC and ERC selectively responded to object familiarity, while the PHC responded to both object and scene familiarity. The amygdala only responded to familiarity memory for faces. The hippocampus did not respond to stimulus familiarity for any of the three types of stimuli, but it did respond to recollection for all three types of stimuli. This was true even when recollection was contrasted to equally accurate familiarity. Overall, the findings suggest that the role of the MTL neocortices and the amygdala in familiarity-based recognition depends on the kind of stimulus in memory, whereas the role of the hippocampus in recollection is independent of the type of cuing stimulus.",
keywords = "recognition memory, parahippocampal cortex, perirhinal cortex, entorhinal cortex, amygdala",
author = "Alex Kafkas and Migo, {Ellen M.} and Morris, {Robin G.} and Kopelman, {Michael D.} and Daniela Montaldi and Mayes, {Andrew R.}",
year = "2017",
month = "2",
day = "1",
doi = "10.1002/hipo.22683",
language = "English",
volume = "27",
pages = "194--209",
journal = "Hippocampus",
issn = "1050-9631",
publisher = "Wiley-Liss Inc.",
number = "2",

}

RIS (suitable for import to EndNote) Download

TY - JOUR

T1 - Material Specificity Drives Medial Temporal Lobe Familiarity But Not Hippocampal Recollection

AU - Kafkas, Alex

AU - Migo, Ellen M.

AU - Morris, Robin G.

AU - Kopelman, Michael D.

AU - Montaldi, Daniela

AU - Mayes, Andrew R.

PY - 2017/2/1

Y1 - 2017/2/1

N2 - The specific role of the perirhinal (PRC), entorhinal (ERC) and parahippocampal cortices (PHC) in supporting familiarity-based recognition remains unknown. An fMRI study explored whether these medial temporal lobe (MTL) structures responded in the same way or differentially to familiarity as a function of stimulus type at recognition. A secondary aim was to explore whether the hippocampus responds in the same way to equally strong familiarity and recollection and whether this is influenced by the kind of stimulus involved. Univariate and multivariate analyses revealed that familiarity responses in the PRC, ERC, PHC and the amygdala are material-specific. Specifically, the PRC and ERC selectively responded to object familiarity, while the PHC responded to both object and scene familiarity. The amygdala only responded to familiarity memory for faces. The hippocampus did not respond to stimulus familiarity for any of the three types of stimuli, but it did respond to recollection for all three types of stimuli. This was true even when recollection was contrasted to equally accurate familiarity. Overall, the findings suggest that the role of the MTL neocortices and the amygdala in familiarity-based recognition depends on the kind of stimulus in memory, whereas the role of the hippocampus in recollection is independent of the type of cuing stimulus.

AB - The specific role of the perirhinal (PRC), entorhinal (ERC) and parahippocampal cortices (PHC) in supporting familiarity-based recognition remains unknown. An fMRI study explored whether these medial temporal lobe (MTL) structures responded in the same way or differentially to familiarity as a function of stimulus type at recognition. A secondary aim was to explore whether the hippocampus responds in the same way to equally strong familiarity and recollection and whether this is influenced by the kind of stimulus involved. Univariate and multivariate analyses revealed that familiarity responses in the PRC, ERC, PHC and the amygdala are material-specific. Specifically, the PRC and ERC selectively responded to object familiarity, while the PHC responded to both object and scene familiarity. The amygdala only responded to familiarity memory for faces. The hippocampus did not respond to stimulus familiarity for any of the three types of stimuli, but it did respond to recollection for all three types of stimuli. This was true even when recollection was contrasted to equally accurate familiarity. Overall, the findings suggest that the role of the MTL neocortices and the amygdala in familiarity-based recognition depends on the kind of stimulus in memory, whereas the role of the hippocampus in recollection is independent of the type of cuing stimulus.

KW - recognition memory

KW - parahippocampal cortex

KW - perirhinal cortex

KW - entorhinal cortex

KW - amygdala

UR - http://www.scopus.com/inward/record.url?scp=85009164514&partnerID=8YFLogxK

U2 - 10.1002/hipo.22683

DO - 10.1002/hipo.22683

M3 - Article

AN - SCOPUS:85009164514

VL - 27

SP - 194

EP - 209

JO - Hippocampus

JF - Hippocampus

SN - 1050-9631

IS - 2

ER -

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