Maternal-placental syndrome and future risk of accelerated cardiovascular events in Parous Swedish women with systemic lupus erythematosus-a population-based retrospective cohort study with time-to-event analysis

May Ching Soh; Fadia Dib; Catherine Nelson-Piercy; Magnus Westgren; Lesley McCowan; Dharmintra Pasupathy

doi:10.1093/rheumatology/kew043

Maternal-placental syndrome and future risk of accelerated cardiovascular events in Parous Swedish women with systemic lupus erythematosus-a population-based retrospective cohort study with time-to-event analysis

May Ching Soh, Fadia Dib, Catherine Nelson-Piercy, Magnus Westgren, Lesley McCowan, Dharmintra Pasupathy^*

^*Corresponding author for this work

Women & Children's Health

Research output: Contribution to journal › Article › peer-review

12 Citations (Scopus)

Abstract

Objectives. Women with SLE are at increased risk of cardiovascular events (CVEs), but a relationship with traditional cardiovascular and SLE-specific risk factors has not been established. In unselected populations, adverse pregnancy outcomes linked to maternal-placental syndrome (MPS) are associated with an increased risk of CVEs. However, the effect of MPS on CVEs is unknown in women with SLE. The aim of this study was to determine if MPS increased the risk and accelerated the development of CVEs in women with SLE. Methods. Utilizing Swedish population registries, parous women with SLE were identified. Exposures were the following: MPS defined as hypertensive disorders of pregnancy; small-for-gestational-age; placental abruption and stillbirth; and preterm delivery

Original language	English
Article number	kew043
Pages (from-to)	1235-1242
Number of pages	8
Journal	Rheumatology
Volume	55
Issue number	7
Early online date	25 Mar 2016
DOIs	https://doi.org/10.1093/rheumatology/kew043
Publication status	Published - 1 Jul 2016

Keywords

Cardiovascular events
Cardiovascular survival
Growth restriction
Maternal-placental syndrome
Population-based
Pre-eclampsia
Pregnancy complications
Preterm delivery
SLE
Small for gestational age

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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Soh, M. C., Dib, F., Nelson-Piercy, C., Westgren, M., McCowan, L., & Pasupathy, D. (2016). Maternal-placental syndrome and future risk of accelerated cardiovascular events in Parous Swedish women with systemic lupus erythematosus-a population-based retrospective cohort study with time-to-event analysis. Rheumatology, 55(7), 1235-1242. Article kew043. https://doi.org/10.1093/rheumatology/kew043

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title = "Maternal-placental syndrome and future risk of accelerated cardiovascular events in Parous Swedish women with systemic lupus erythematosus-a population-based retrospective cohort study with time-to-event analysis",

abstract = "Objectives. Women with SLE are at increased risk of cardiovascular events (CVEs), but a relationship with traditional cardiovascular and SLE-specific risk factors has not been established. In unselected populations, adverse pregnancy outcomes linked to maternal-placental syndrome (MPS) are associated with an increased risk of CVEs. However, the effect of MPS on CVEs is unknown in women with SLE. The aim of this study was to determine if MPS increased the risk and accelerated the development of CVEs in women with SLE. Methods. Utilizing Swedish population registries, parous women with SLE were identified. Exposures were the following: MPS defined as hypertensive disorders of pregnancy; small-for-gestational-age; placental abruption and stillbirth; and preterm delivery",

keywords = "Cardiovascular events, Cardiovascular survival, Growth restriction, Maternal-placental syndrome, Population-based, Pre-eclampsia, Pregnancy complications, Preterm delivery, SLE, Small for gestational age",

author = "Soh, {May Ching} and Fadia Dib and Catherine Nelson-Piercy and Magnus Westgren and Lesley McCowan and Dharmintra Pasupathy",

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Soh, MC, Dib, F , Nelson-Piercy, C, Westgren, M, McCowan, L & Pasupathy, D 2016, 'Maternal-placental syndrome and future risk of accelerated cardiovascular events in Parous Swedish women with systemic lupus erythematosus-a population-based retrospective cohort study with time-to-event analysis', Rheumatology, vol. 55, no. 7, kew043, pp. 1235-1242. https://doi.org/10.1093/rheumatology/kew043

Maternal-placental syndrome and future risk of accelerated cardiovascular events in Parous Swedish women with systemic lupus erythematosus-a population-based retrospective cohort study with time-to-event analysis. / Soh, May Ching; Dib, Fadia ; Nelson-Piercy, Catherine et al.
In: Rheumatology, Vol. 55, No. 7, kew043, 01.07.2016, p. 1235-1242.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Maternal-placental syndrome and future risk of accelerated cardiovascular events in Parous Swedish women with systemic lupus erythematosus-a population-based retrospective cohort study with time-to-event analysis

AU - Soh, May Ching

AU - Dib, Fadia

AU - Nelson-Piercy, Catherine

AU - Westgren, Magnus

AU - McCowan, Lesley

AU - Pasupathy, Dharmintra

PY - 2016/7/1

Y1 - 2016/7/1

N2 - Objectives. Women with SLE are at increased risk of cardiovascular events (CVEs), but a relationship with traditional cardiovascular and SLE-specific risk factors has not been established. In unselected populations, adverse pregnancy outcomes linked to maternal-placental syndrome (MPS) are associated with an increased risk of CVEs. However, the effect of MPS on CVEs is unknown in women with SLE. The aim of this study was to determine if MPS increased the risk and accelerated the development of CVEs in women with SLE. Methods. Utilizing Swedish population registries, parous women with SLE were identified. Exposures were the following: MPS defined as hypertensive disorders of pregnancy; small-for-gestational-age; placental abruption and stillbirth; and preterm delivery

AB - Objectives. Women with SLE are at increased risk of cardiovascular events (CVEs), but a relationship with traditional cardiovascular and SLE-specific risk factors has not been established. In unselected populations, adverse pregnancy outcomes linked to maternal-placental syndrome (MPS) are associated with an increased risk of CVEs. However, the effect of MPS on CVEs is unknown in women with SLE. The aim of this study was to determine if MPS increased the risk and accelerated the development of CVEs in women with SLE. Methods. Utilizing Swedish population registries, parous women with SLE were identified. Exposures were the following: MPS defined as hypertensive disorders of pregnancy; small-for-gestational-age; placental abruption and stillbirth; and preterm delivery

KW - Cardiovascular events

KW - Cardiovascular survival

KW - Growth restriction

KW - Maternal-placental syndrome

KW - Population-based

KW - Pre-eclampsia

KW - Pregnancy complications

KW - Preterm delivery

KW - SLE

KW - Small for gestational age

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Soh MC, Dib F , Nelson-Piercy C, Westgren M, McCowan L, Pasupathy D. Maternal-placental syndrome and future risk of accelerated cardiovascular events in Parous Swedish women with systemic lupus erythematosus-a population-based retrospective cohort study with time-to-event analysis. Rheumatology. 2016 Jul 1;55(7):1235-1242. kew043. Epub 2016 Mar 25. doi: 10.1093/rheumatology/kew043

Maternal-placental syndrome and future risk of accelerated cardiovascular events in Parous Swedish women with systemic lupus erythematosus-a population-based retrospective cohort study with time-to-event analysis

Abstract

Keywords

UN SDGs

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