TY - JOUR
T1 - Measurements of volumetric bone mineral density in the mandible do not predict spinal osteoporosis
AU - Guo, Zhe
AU - Du, Xia
AU - Wang, Ling
AU - Li, Kai
AU - Jiao, Jun
AU - Guglielmi, Giuseppe
AU - Zhurakivska, Khrystyna
AU - Lo Muzio, Lorenzo
AU - Blake, Glen M.
AU - Cheng, Xiaoguang
PY - 2020/3/1
Y1 - 2020/3/1
N2 - OBJECTIVE: The objective of this study was to determine whether the trabecular volumetric Bone Mineral Density (vBMD) of the middle, body and angle of the mandible correlates with vBMD of the cervical and lumbar vertebrae in a Chinese population. METHODS AND MATERIALS: 661 subjects (270 males, 391 females), ranging from 20 to 59 years of age, were recruited for vBMD measurements by quantitative CT (QCT). Basic information (age, height and weight), vBMD of the mandible (middle, body and angle sites), and vBMD of the cervical and lumbar vertebrae were recorded. Spearman's rank correlation test was used to investigate the association of mandibular with vertebral vBMD. RESULTS: The study cohort comprised 661 subjects: 270 (41%) males, 391 (59%) females. Median age in males was 40 (range, 21-59) years. Median age in females was 41 (range, 20-59) years. Values of the Spearman correlation coefficient between mandibular and vertebral vBMD ranged from R = 0.048 to 0.141. In males, the three correlation coefficients between mandibular and cervical vBMD (middle: R = 0.138; body: R = 0.126; angle: R = 0.122) were all statistically significant (p < 0.05). In females, the correlation between the middle mandibular site and cervical site was statistically significant (R = 0.141, p < 0.01). None of the other correlations examined were statistically significant. CONCLUSION: In this study population, mandibular vBMD was at best weakly correlated with cervical and lumbar vertebral vBMD, indicating that mandibular vBMD should be measured independently for the assessment of mandibular bone status.
AB - OBJECTIVE: The objective of this study was to determine whether the trabecular volumetric Bone Mineral Density (vBMD) of the middle, body and angle of the mandible correlates with vBMD of the cervical and lumbar vertebrae in a Chinese population. METHODS AND MATERIALS: 661 subjects (270 males, 391 females), ranging from 20 to 59 years of age, were recruited for vBMD measurements by quantitative CT (QCT). Basic information (age, height and weight), vBMD of the mandible (middle, body and angle sites), and vBMD of the cervical and lumbar vertebrae were recorded. Spearman's rank correlation test was used to investigate the association of mandibular with vertebral vBMD. RESULTS: The study cohort comprised 661 subjects: 270 (41%) males, 391 (59%) females. Median age in males was 40 (range, 21-59) years. Median age in females was 41 (range, 20-59) years. Values of the Spearman correlation coefficient between mandibular and vertebral vBMD ranged from R = 0.048 to 0.141. In males, the three correlation coefficients between mandibular and cervical vBMD (middle: R = 0.138; body: R = 0.126; angle: R = 0.122) were all statistically significant (p < 0.05). In females, the correlation between the middle mandibular site and cervical site was statistically significant (R = 0.141, p < 0.01). None of the other correlations examined were statistically significant. CONCLUSION: In this study population, mandibular vBMD was at best weakly correlated with cervical and lumbar vertebral vBMD, indicating that mandibular vBMD should be measured independently for the assessment of mandibular bone status.
KW - Bone density
KW - Computed tomography
KW - Mandible
KW - Spine
UR - http://www.scopus.com/inward/record.url?scp=85079343188&partnerID=8YFLogxK
U2 - 10.1259/dmfr.20190280
DO - 10.1259/dmfr.20190280
M3 - Article
C2 - 31718273
AN - SCOPUS:85079343188
SN - 0250-832X
VL - 49
JO - Dento maxillo facial radiology
JF - Dento maxillo facial radiology
IS - 3
M1 - 20190280
ER -