Metabolic activation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and DNA adduct formation depends on p53: studies in Trp53(+/+), Trp53(+/-) and Trp53(-/-) mice

Annette M Krais, Ewoud N Speksnijder, Joost P M Melis, Rajinder Singh, Anna Caldwell, Gonçalo Gamboa da Costa, Mirjam Luijten, David H Phillips, Volker M Arlt

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Biochemistry, Genetics and Molecular Biology

Pharmacology, Toxicology and Pharmaceutical Science