Microfluidic radiolabelling of the chelator DOTA with gallium-68 at room temperature for use in PET imaging

H. A. Bignell, M. D. Tarn, B. P. Burke, N. Pamme, S. J. Archibald*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference paperpeer-review

2 Citations (Scopus)

Abstract

We present, for the first time, the quantitative radiolabelling at room temperature of the 'workhorse' bifunctional chelator, 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA) with the gallium-68 radiometal for the production of positron emission tomography (PET) radiopharmaceuticals using microfluidic technology.

Original languageEnglish
Title of host publication20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016
PublisherChemical and Biological Microsystems Society
Pages1577-1578
Number of pages2
ISBN (Electronic)9780979806490
Publication statusPublished - 2016
Event20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016 - Dublin, Ireland
Duration: 9 Oct 201613 Oct 2016

Publication series

Name20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016

Conference

Conference20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016
Country/TerritoryIreland
CityDublin
Period9/10/201613/10/2016

Keywords

  • Bifunctional chelators
  • Gallium-68
  • Microreactors
  • Positron emission tomography (PET) imaging
  • Radiolabelling
  • Radiometals
  • Staggered herringbone micromixers

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