Microsphere Solid-State Biolasers

TY - JOUR

T1 - Microsphere Solid-State Biolasers

AU - Ta, Van Duong

AU - Caixeiro, Soraya

AU - Fernandes, Francisco M.

AU - Sapienza, Riccardo

PY - 2017/4/18

Y1 - 2017/4/18

N2 - Biolasers obtained from biomaterials are attracting a wealth of interest for their potential as future biosensors with enhanced sensitivity, and advanced cell tracking. Here, miniature biolasers are reported, which are formed by bovine serum albumin (BSA) protein and biosourced polysaccharides derived from land plants such as cellulose and pectin. Using a green processing route aided by simple emulsions, solid-state microspheres with diameters of 15-100 μm are fabricated and utilized as whispering gallery mode lasers with thresholds of a few μJ mm-2 and quality factors of up to 3000. Furthermore, BSA microlasers are found to be compatible with cell growth and resistant to the aqueous environment of cell culture media. This environmentally friendly and biocompatible design shows promise for future implantable biosensing devices opening a path between laser science and medicine.

AB - Biolasers obtained from biomaterials are attracting a wealth of interest for their potential as future biosensors with enhanced sensitivity, and advanced cell tracking. Here, miniature biolasers are reported, which are formed by bovine serum albumin (BSA) protein and biosourced polysaccharides derived from land plants such as cellulose and pectin. Using a green processing route aided by simple emulsions, solid-state microspheres with diameters of 15-100 μm are fabricated and utilized as whispering gallery mode lasers with thresholds of a few μJ mm-2 and quality factors of up to 3000. Furthermore, BSA microlasers are found to be compatible with cell growth and resistant to the aqueous environment of cell culture media. This environmentally friendly and biocompatible design shows promise for future implantable biosensing devices opening a path between laser science and medicine.

KW - Biomaterial

KW - Lasers

KW - Polysaccharides

KW - Protein

KW - Whispering gallery mode

UR - http://www.scopus.com/inward/record.url?scp=85015190118&partnerID=8YFLogxK

U2 - 10.1002/adom.201601022

DO - 10.1002/adom.201601022

M3 - Article

AN - SCOPUS:85015190118

SN - 2195-1071

VL - 5

SP - 1

EP - 6

JO - Advanced Optical Materials

JF - Advanced Optical Materials

IS - 8

M1 - 1601022

ER -