Microstructural and volumetric abnormalities of the putamen in juvenile myoclonic epilepsy

Simon S Keller; Tobias Ahrens; Siawoosh Mohammadi; Gabriel Möddel; Harald Kugel; E Bernd Ringelstein; Michael Deppe

doi:10.1111/j.1528-1167.2011.03117.x

Microstructural and volumetric abnormalities of the putamen in juvenile myoclonic epilepsy

Simon S Keller, Tobias Ahrens, Siawoosh Mohammadi, Gabriel Möddel, Harald Kugel, E Bernd Ringelstein, Michael Deppe

Research output: Contribution to journal › Article › peer-review

70 Citations (Scopus)

Abstract

Patients with juvenile myoclonic epilepsy (JME) show evidence of microstructural white matter (WM) damage of thalamocortical fiber tracts and changes of blood oxygen level dependent (BOLD) signal in a striatothalamocortical network. The objective of the present study was to investigate microstructural and volumetric alterations of the putamen in patients with JME using diffusion tensor imaging (DTI) and conventional magnetic resonance imaging (MRI).

Original language	English
Pages (from-to)	1715-24
Number of pages	10
Journal	Epilepsia
Volume	52
Issue number	9
DOIs	https://doi.org/10.1111/j.1528-1167.2011.03117.x
Publication status	Published - Sept 2011

Keywords

Nerve Fibers, Myelinated
Magnetic Resonance Imaging
Young Adult
Analysis of Variance
Anisotropy
Humans
Myoclonic Epilepsy, Juvenile
Thalamus
Cerebral Cortex
Diffusion Magnetic Resonance Imaging
Brain Mapping
Adult
Case-Control Studies
Adolescent
Female
Male

Access to Document

10.1111/j.1528-1167.2011.03117.x

Cite this

@article{59c3e464aaee44ee882d485eec8fbc97,

title = "Microstructural and volumetric abnormalities of the putamen in juvenile myoclonic epilepsy",

abstract = "Patients with juvenile myoclonic epilepsy (JME) show evidence of microstructural white matter (WM) damage of thalamocortical fiber tracts and changes of blood oxygen level dependent (BOLD) signal in a striatothalamocortical network. The objective of the present study was to investigate microstructural and volumetric alterations of the putamen in patients with JME using diffusion tensor imaging (DTI) and conventional magnetic resonance imaging (MRI).",

keywords = "Nerve Fibers, Myelinated, Magnetic Resonance Imaging, Young Adult, Analysis of Variance, Anisotropy, Humans, Myoclonic Epilepsy, Juvenile, Thalamus, Cerebral Cortex, Diffusion Magnetic Resonance Imaging, Brain Mapping, Adult, Case-Control Studies, Adolescent, Female, Male",

author = "Keller, {Simon S} and Tobias Ahrens and Siawoosh Mohammadi and Gabriel M{\"o}ddel and Harald Kugel and Ringelstein, {E Bernd} and Michael Deppe",

note = "Wiley Periodicals, Inc. {\textcopyright} 2011 International League Against Epilepsy.",

year = "2011",

month = sep,

doi = "10.1111/j.1528-1167.2011.03117.x",

language = "English",

volume = "52",

pages = "1715--24",

journal = "Epilepsia",

publisher = "Wiley-Blackwell",

number = "9",

}

TY - JOUR

T1 - Microstructural and volumetric abnormalities of the putamen in juvenile myoclonic epilepsy

AU - Keller, Simon S

AU - Ahrens, Tobias

AU - Mohammadi, Siawoosh

AU - Möddel, Gabriel

AU - Kugel, Harald

AU - Ringelstein, E Bernd

AU - Deppe, Michael

PY - 2011/9

Y1 - 2011/9

N2 - Patients with juvenile myoclonic epilepsy (JME) show evidence of microstructural white matter (WM) damage of thalamocortical fiber tracts and changes of blood oxygen level dependent (BOLD) signal in a striatothalamocortical network. The objective of the present study was to investigate microstructural and volumetric alterations of the putamen in patients with JME using diffusion tensor imaging (DTI) and conventional magnetic resonance imaging (MRI).

AB - Patients with juvenile myoclonic epilepsy (JME) show evidence of microstructural white matter (WM) damage of thalamocortical fiber tracts and changes of blood oxygen level dependent (BOLD) signal in a striatothalamocortical network. The objective of the present study was to investigate microstructural and volumetric alterations of the putamen in patients with JME using diffusion tensor imaging (DTI) and conventional magnetic resonance imaging (MRI).

KW - Nerve Fibers, Myelinated

KW - Magnetic Resonance Imaging

KW - Young Adult

KW - Analysis of Variance

KW - Anisotropy

KW - Humans

KW - Myoclonic Epilepsy, Juvenile

KW - Thalamus

KW - Cerebral Cortex

KW - Diffusion Magnetic Resonance Imaging

KW - Brain Mapping

KW - Adult

KW - Case-Control Studies

KW - Adolescent

KW - Female

KW - Male

U2 - 10.1111/j.1528-1167.2011.03117.x

DO - 10.1111/j.1528-1167.2011.03117.x

M3 - Article

C2 - 21635242

VL - 52

SP - 1715

EP - 1724

JO - Epilepsia

JF - Epilepsia

IS - 9

ER -

Microstructural and volumetric abnormalities of the putamen in juvenile myoclonic epilepsy

Abstract

Keywords

Access to Document

Fingerprint

Cite this