Microwave breast tumor detection and size estimation using contrast-agent-loaded magnetotactic bacteria

Yifan Chen, Panagiotis Kosmas, Sylvain Martel

Research output: Chapter in Book/Report/Conference proceedingConference paperpeer-review

11 Citations (Scopus)

Abstract

We propose a new approach to microwave breast tumor detection based on the use of bio-compatible flagellated magnetotactic bacteria (MTB). Previous work has shown that the directions and speeds of these bacterial microrobots adapted to operate in human microvasculature can be guided along preplanned paths deep inside the human body through external magnetic fields. Furthermore, a microwave contrast agent can be loaded onto MTB to alter the dielectric properties of tissues near the agent. Based on these two phenomena, we illustrate how multiple agglomerations of MTB released into human breast could be tracked simultaneously and monitored using differential microwave imaging (DMI) techniques. We also present novel strategies to detect and localize a breast cancerous mass as well as estimate its size through this new DMI-trackable bacterial propulsion and steering approach, and use an anatomically realistic breast model as a testbed to verify the feasibility of this breast cancer diagnostic technique.
Original languageEnglish
Title of host publicationEngineering in Medicine and Biology Society (EMBC), 2013 35th Annual International Conference of the IEEE
PublisherIEEE
Pages5481-5484
Number of pages4
ISBN (Print)9781457702150
DOIs
Publication statusPublished - 2013
Event2013 35th Annual International Conference of the IEEE - Osaka , Japan
Duration: 3 Jul 20137 Jul 2013

Conference

Conference2013 35th Annual International Conference of the IEEE
Country/TerritoryJapan
CityOsaka
Period3/07/20137/07/2013

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