Minimally invasive photoacoustic imaging: Current status and future perspectives

TY - JOUR

T1 - Minimally invasive photoacoustic imaging

T2 - Current status and future perspectives

AU - Zhao, Tianrui

AU - Desjardins, Adrien E.

AU - Ourselin, Sebastien

AU - Vercauteren, Tom

AU - Xia, Wenfeng

PY - 2019/12/1

Y1 - 2019/12/1

N2 - Photoacoustic imaging (PAI) is an emerging biomedical imaging modality that is based on optical absorption contrast, capable of revealing distinct spectroscopic signatures of tissue at high spatial resolution and large imaging depths. However, clinical applications of conventional non-invasive PAI systems have been restricted to examinations of tissues at depths less than a few cm due to strong light attenuation. Minimally invasive photoacoustic imaging (miPAI) has greatly extended the landscape of PAI by delivering excitation light within tissue through miniature fibre-optic probes. In the past decade, various miPAI systems have been developed with demonstrated applicability in several clinical fields. In this article, we present an overview of the current status of miPAI and our thoughts on future perspectives.

AB - Photoacoustic imaging (PAI) is an emerging biomedical imaging modality that is based on optical absorption contrast, capable of revealing distinct spectroscopic signatures of tissue at high spatial resolution and large imaging depths. However, clinical applications of conventional non-invasive PAI systems have been restricted to examinations of tissues at depths less than a few cm due to strong light attenuation. Minimally invasive photoacoustic imaging (miPAI) has greatly extended the landscape of PAI by delivering excitation light within tissue through miniature fibre-optic probes. In the past decade, various miPAI systems have been developed with demonstrated applicability in several clinical fields. In this article, we present an overview of the current status of miPAI and our thoughts on future perspectives.

KW - Interventional photoacoustic imaging

KW - Minimally invasive procedures

KW - Multi-modal imaging

KW - Photoacoustic computed tomography

KW - Photoacoustic endoscopy

KW - Photoacoustic imaging

KW - Photoacoustic microscopy

UR - http://www.scopus.com/inward/record.url?scp=85076011233&partnerID=8YFLogxK

U2 - 10.1016/j.pacs.2019.100146

DO - 10.1016/j.pacs.2019.100146

M3 - Review article

AN - SCOPUS:85076011233

SN - 2213-5979

VL - 16

JO - Photoacoustics

JF - Photoacoustics

M1 - 100146

ER -