Mining the PDB for Tractable Cases Where X-ray Crystallography Combined with Fragment Screens Can Be Used to Systematically Design Protein-Protein Inhibitors: Two Test Cases Illustrated by IL1β-IL1R and p38α-TAB1 Complexes

Charlie Nichols, Joseph Ng, Annika Keshu, Geoff Kelly, Maria R. Conte, Michael S. Marber, Franca Fraternali, Gian F. De Nicola

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Biochemistry, Genetics and Molecular Biology

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