Modelling gene networks at different organisational levels

T Schlitt, A Brazma

Research output: Contribution to journalLiterature reviewpeer-review

45 Citations (Scopus)


Approaches to modelling gene regulation networks can be categorized, according to increasing detail, as network parts lists, network topology models, network control logic models, or dynamic models. We discuss the current state of the art for each of these approaches. There is a gap between the parts list and topology models on one hand, and control logic and dynamic models on the other hand. The first two classes of models have reached a genome-wide scale, while for the other model classes high throughput technologies are yet to make a major impact. (c) 2005 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved
Original languageEnglish
Pages (from-to)1859 - 1866
Number of pages8
JournalFEBS Letters
Issue number8
Publication statusPublished - 21 Mar 2005


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