TY - JOUR
T1 - Modulating the gut-liver axis and the pivotal role of the faecal microbiome in cirrhosis
AU - Woodhouse, Charlotte
AU - Singanayagam, Arjuna
AU - Patel, Vishal C.
PY - 2020/9/1
Y1 - 2020/9/1
N2 - Cirrhosis is associated with intestinal dysbiosis, with specific alterations in the gut microbiota linked to particular aetiologies and manifestations of the disease. We review the role of the gut microbiome and the importance of the intestinal barrier in cirrhosis, provide an overview of the terminology and techniques relevant to this emerging area, and discuss the latest developments in therapies targeting the gut-liver axis.
AB - Cirrhosis is associated with intestinal dysbiosis, with specific alterations in the gut microbiota linked to particular aetiologies and manifestations of the disease. We review the role of the gut microbiome and the importance of the intestinal barrier in cirrhosis, provide an overview of the terminology and techniques relevant to this emerging area, and discuss the latest developments in therapies targeting the gut-liver axis.
KW - cirrhosis
KW - dysbiosis
KW - faecal microbial transplantation
KW - gut–liver axis
KW - Microbiota
UR - http://www.scopus.com/inward/record.url?scp=85091054246&partnerID=8YFLogxK
U2 - 10.7861/clinmed.2020-0676
DO - 10.7861/clinmed.2020-0676
M3 - Article
C2 - 32934044
AN - SCOPUS:85091054246
SN - 1470-2118
VL - 20
SP - 490
EP - 500
JO - Clinical medicine (London, England)
JF - Clinical medicine (London, England)
IS - 5
ER -