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Modulating the gut-liver axis and the pivotal role of the faecal microbiome in cirrhosis

Research output: Contribution to journalArticle

Charlotte Woodhouse, Arjuna Singanayagam, Vishal C. Patel

Original languageEnglish
Pages (from-to)490-500
Number of pages11
JournalClinical medicine (London, England)
Volume20
Issue number5
DOIs
Published1 Sep 2020

King's Authors

Abstract

Cirrhosis is associated with intestinal dysbiosis, with specific alterations in the gut microbiota linked to particular aetiologies and manifestations of the disease. We review the role of the gut microbiome and the importance of the intestinal barrier in cirrhosis, provide an overview of the terminology and techniques relevant to this emerging area, and discuss the latest developments in therapies targeting the gut-liver axis.

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