Monitoring Criminal Activity through Invisible Fluorescent “Peptide Coding” Taggants

James Gooch; Hilary Goh; Barbara Elizabeth Daniel; Vincenzo Abbate; Nunzianda Frascione

doi:10.1021/acs.analchem.6b00263

Monitoring Criminal Activity through Invisible Fluorescent “Peptide Coding” Taggants

James Gooch, Hilary Goh, Barbara Elizabeth Daniel, Vincenzo Abbate, Nunzianda Frascione

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Abstract

Complementing the demand for effective crime reduction measures are the increasing availability of commercial forensic “taggants”, which may be used to physically mark an object in order to make it uniquely identifiable. This study explores the use of a novel “peptide coding” reagents to establish evidence of contact transfer during criminal activity. The reagent, containing a fluorophore dispersed within an oil-based medium, also includes a unique synthetic peptide sequence that acts as a traceable “code” to identify the origin of the taggant. The reagent is detectable through its fluorescent properties, which then allows the peptide to be recovered by swabbing and extracted for electrospray ionization-mass spectrometry (ESI-MS) analysis via a simple liquid–liquid extraction procedure. The performance of the reagent in variable conditions that mimic the limits of a real world use are investigated.

Original language	English
Pages (from-to)	4169-4582
Journal	Analytical Chemistry
Volume	88
Issue number	8
Early online date	31 Mar 2016
DOIs	https://doi.org/10.1021/acs.analchem.6b00263
Publication status	Published - 19 Apr 2016

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Monitoring Criminal Activity through_GOOCH_Accepted24March2016_GREEN AAMAccepted author manuscript, 739 KB

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AU - Frascione, Nunzianda

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Monitoring Criminal Activity through Invisible Fluorescent “Peptide Coding” Taggants

Abstract

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