MONOLITHS AS MICROREACTORS FOR 68GA PROCESSING AND RADIOLABELING

Ping He; Andrew W. Beavis; Nicole Pamme; Stephen J. Archibald

MONOLITHS AS MICROREACTORS FOR ⁶⁸GA PROCESSING AND RADIOLABELING

Ping He, Andrew W. Beavis, Nicole Pamme, Stephen J. Archibald^*

^*Corresponding author for this work

Imaging Chemistry & Biology

Research output: Chapter in Book/Report/Conference proceeding › Conference paper › peer-review

Abstract

A novel protocol based on a cation-exchange monolith has been developed to not only quantitatively trap and release the ⁶⁸Ga generator eluate, but also act as microreactor for subsequent in situ radiolabeling of chelators. The monolith-based system has the potential for dose-on-demand radiotracer synthesis.

Original language	English
Title of host publication	MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences
Publisher	Chemical and Biological Microsystems Society
Pages	1131-1132
Number of pages	2
ISBN (Electronic)	9781733419031
Publication status	Published - 2021
Event	25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2021 - Palm Springs, Virtual, United States Duration: 10 Oct 2021 → 14 Oct 2021

Publication series

Name	MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences

Conference

Conference	25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2021
Country/Territory	United States
City	Palm Springs, Virtual
Period	10/10/2021 → 14/10/2021

Keywords

Flow Chemistry
Monolith
Radiochemistry
Radiopharmaceutical

Cite this

He, P., Beavis, A. W., Pamme, N., & Archibald, S. J. (2021). MONOLITHS AS MICROREACTORS FOR ⁶⁸GA PROCESSING AND RADIOLABELING. In MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences (pp. 1131-1132). (MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences). Chemical and Biological Microsystems Society.

He, Ping ; Beavis, Andrew W. ; Pamme, Nicole et al. / MONOLITHS AS MICROREACTORS FOR ⁶⁸GA PROCESSING AND RADIOLABELING. MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Chemical and Biological Microsystems Society, 2021. pp. 1131-1132 (MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences).

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title = "MONOLITHS AS MICROREACTORS FOR 68GA PROCESSING AND RADIOLABELING",

abstract = "A novel protocol based on a cation-exchange monolith has been developed to not only quantitatively trap and release the 68Ga generator eluate, but also act as microreactor for subsequent in situ radiolabeling of chelators. The monolith-based system has the potential for dose-on-demand radiotracer synthesis.",

keywords = "Flow Chemistry, Monolith, Radiochemistry, Radiopharmaceutical",

author = "Ping He and Beavis, {Andrew W.} and Nicole Pamme and Archibald, {Stephen J.}",

note = "Publisher Copyright: {\textcopyright} 2021 MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences. All rights reserved.; 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2021 ; Conference date: 10-10-2021 Through 14-10-2021",

year = "2021",

language = "English",

series = "MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences",

publisher = "Chemical and Biological Microsystems Society",

pages = "1131--1132",

booktitle = "MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences",

}

He, P, Beavis, AW, Pamme, N & Archibald, SJ 2021, MONOLITHS AS MICROREACTORS FOR ⁶⁸GA PROCESSING AND RADIOLABELING. in MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences. MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, Chemical and Biological Microsystems Society, pp. 1131-1132, 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2021, Palm Springs, Virtual, United States, 10/10/2021.

MONOLITHS AS MICROREACTORS FOR ⁶⁸GA PROCESSING AND RADIOLABELING. / He, Ping; Beavis, Andrew W.; Pamme, Nicole et al.
MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Chemical and Biological Microsystems Society, 2021. p. 1131-1132 (MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences).

Research output: Chapter in Book/Report/Conference proceeding › Conference paper › peer-review

TY - CHAP

T1 - MONOLITHS AS MICROREACTORS FOR 68GA PROCESSING AND RADIOLABELING

AU - He, Ping

AU - Beavis, Andrew W.

AU - Pamme, Nicole

AU - Archibald, Stephen J.

PY - 2021

Y1 - 2021

N2 - A novel protocol based on a cation-exchange monolith has been developed to not only quantitatively trap and release the 68Ga generator eluate, but also act as microreactor for subsequent in situ radiolabeling of chelators. The monolith-based system has the potential for dose-on-demand radiotracer synthesis.

AB - A novel protocol based on a cation-exchange monolith has been developed to not only quantitatively trap and release the 68Ga generator eluate, but also act as microreactor for subsequent in situ radiolabeling of chelators. The monolith-based system has the potential for dose-on-demand radiotracer synthesis.

KW - Flow Chemistry

KW - Monolith

KW - Radiochemistry

KW - Radiopharmaceutical

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M3 - Conference paper

AN - SCOPUS:85136953445

T3 - MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences

SP - 1131

EP - 1132

BT - MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences

PB - Chemical and Biological Microsystems Society

T2 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2021

Y2 - 10 October 2021 through 14 October 2021

ER -

He P, Beavis AW, Pamme N, Archibald SJ. MONOLITHS AS MICROREACTORS FOR ⁶⁸GA PROCESSING AND RADIOLABELING. In MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Chemical and Biological Microsystems Society. 2021. p. 1131-1132. (MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences).