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Motion-corrected simultaneous cardiac positron emission tomography and coronary MR angiography with high acquisition efficiency

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Motion-corrected simultaneous cardiac positron emission tomography and coronary MR angiography with high acquisition efficiency. / Munoz, Camila; Neji, Radhouene; Cruz, Gastão; Mallia, Andrew; Jeljeli, Sami; Reader, Andrew J; Botnar, Rene M; Prieto, Claudia.

In: Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine, 20.04.2017.

Research output: Contribution to journalArticle

Harvard

Munoz, C, Neji, R, Cruz, G, Mallia, A, Jeljeli, S, Reader, AJ, Botnar, RM & Prieto, C 2017, 'Motion-corrected simultaneous cardiac positron emission tomography and coronary MR angiography with high acquisition efficiency', Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. https://doi.org/10.1002/mrm.26690

APA

Munoz, C., Neji, R., Cruz, G., Mallia, A., Jeljeli, S., Reader, A. J., Botnar, R. M., & Prieto, C. (2017). Motion-corrected simultaneous cardiac positron emission tomography and coronary MR angiography with high acquisition efficiency. Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. https://doi.org/10.1002/mrm.26690

Vancouver

Munoz C, Neji R, Cruz G, Mallia A, Jeljeli S, Reader AJ et al. Motion-corrected simultaneous cardiac positron emission tomography and coronary MR angiography with high acquisition efficiency. Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. 2017 Apr 20. https://doi.org/10.1002/mrm.26690

Author

Munoz, Camila ; Neji, Radhouene ; Cruz, Gastão ; Mallia, Andrew ; Jeljeli, Sami ; Reader, Andrew J ; Botnar, Rene M ; Prieto, Claudia. / Motion-corrected simultaneous cardiac positron emission tomography and coronary MR angiography with high acquisition efficiency. In: Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. 2017.

Bibtex Download

@article{b16a969ad8b5429597eff8943c753190,
title = "Motion-corrected simultaneous cardiac positron emission tomography and coronary MR angiography with high acquisition efficiency",
abstract = "PURPOSE: Develop a framework for efficient free-breathing simultaneous whole-heart coronary magnetic resonance angiography (CMRA) and cardiac positron emission tomography (PET) on a 3 Tesla PET-MR system.METHODS: An acquisition that enables nonrigid motion correction of both CMRA and PET has been developed. The proposed method estimates translational motion from low-resolution 2D MR image navigators acquired at each heartbeat and 3D nonrigid respiratory motion between different respiratory bins from the CMRA data itself. Estimated motion is used for correcting the CMRA as well as the emission and attenuation PET data sets to the same respiratory position. The CMRA approach was studied in 10 healthy subjects and compared for both left and right coronary arteries (LCA, RCA) against a reference scan with diaphragmatic navigator gating and tracking. The PET-CMRA approach was tested in 5 oncology patients with (18) F-FDG myocardial uptake. PET images were compared against uncorrected and gated PET reconstructions.RESULTS: For the healthy subjects, no statistically significant differences in vessel length and sharpness (P > 0.01) were observed between the proposed approach and the reference acquisition with navigator gating and tracking, although data acquisition was significantly shorter. The proposed approach improved CMRA vessel sharpness by 37.9% and 49.1% (LCA, RCA) and vessel length by 48.0% and 36.7% (LCA, RCA) in comparison with no motion correction for all the subjects. Motion-corrected PET images showed improved sharpness of the myocardium compared to uncorrected reconstructions and reduced noise compared to gated reconstructions.CONCLUSION: Feasibility of a new respiratory motion-compensated simultaneous cardiac PET-CMRA acquisition has been demonstrated. Magn Reson Med, 2017. {\textcopyright} 2017 The Authors Magnetic Resonance in Medicine published by Wiley Periodicals, Inc. on behalf of International Society for Magnetic Resonance in Medicine.",
author = "Camila Munoz and Radhouene Neji and Gast{\~a}o Cruz and Andrew Mallia and Sami Jeljeli and Reader, {Andrew J} and Botnar, {Rene M} and Claudia Prieto",
note = "{\textcopyright} 2017 The Authors Magnetic Resonance in Medicine published by Wiley Periodicals, Inc. on behalf of International Society for Magnetic Resonance in Medicine.",
year = "2017",
month = apr,
day = "20",
doi = "10.1002/mrm.26690",
language = "English",
journal = "Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine",
issn = "1522-2594",

}

RIS (suitable for import to EndNote) Download

TY - JOUR

T1 - Motion-corrected simultaneous cardiac positron emission tomography and coronary MR angiography with high acquisition efficiency

AU - Munoz, Camila

AU - Neji, Radhouene

AU - Cruz, Gastão

AU - Mallia, Andrew

AU - Jeljeli, Sami

AU - Reader, Andrew J

AU - Botnar, Rene M

AU - Prieto, Claudia

N1 - © 2017 The Authors Magnetic Resonance in Medicine published by Wiley Periodicals, Inc. on behalf of International Society for Magnetic Resonance in Medicine.

PY - 2017/4/20

Y1 - 2017/4/20

N2 - PURPOSE: Develop a framework for efficient free-breathing simultaneous whole-heart coronary magnetic resonance angiography (CMRA) and cardiac positron emission tomography (PET) on a 3 Tesla PET-MR system.METHODS: An acquisition that enables nonrigid motion correction of both CMRA and PET has been developed. The proposed method estimates translational motion from low-resolution 2D MR image navigators acquired at each heartbeat and 3D nonrigid respiratory motion between different respiratory bins from the CMRA data itself. Estimated motion is used for correcting the CMRA as well as the emission and attenuation PET data sets to the same respiratory position. The CMRA approach was studied in 10 healthy subjects and compared for both left and right coronary arteries (LCA, RCA) against a reference scan with diaphragmatic navigator gating and tracking. The PET-CMRA approach was tested in 5 oncology patients with (18) F-FDG myocardial uptake. PET images were compared against uncorrected and gated PET reconstructions.RESULTS: For the healthy subjects, no statistically significant differences in vessel length and sharpness (P > 0.01) were observed between the proposed approach and the reference acquisition with navigator gating and tracking, although data acquisition was significantly shorter. The proposed approach improved CMRA vessel sharpness by 37.9% and 49.1% (LCA, RCA) and vessel length by 48.0% and 36.7% (LCA, RCA) in comparison with no motion correction for all the subjects. Motion-corrected PET images showed improved sharpness of the myocardium compared to uncorrected reconstructions and reduced noise compared to gated reconstructions.CONCLUSION: Feasibility of a new respiratory motion-compensated simultaneous cardiac PET-CMRA acquisition has been demonstrated. Magn Reson Med, 2017. © 2017 The Authors Magnetic Resonance in Medicine published by Wiley Periodicals, Inc. on behalf of International Society for Magnetic Resonance in Medicine.

AB - PURPOSE: Develop a framework for efficient free-breathing simultaneous whole-heart coronary magnetic resonance angiography (CMRA) and cardiac positron emission tomography (PET) on a 3 Tesla PET-MR system.METHODS: An acquisition that enables nonrigid motion correction of both CMRA and PET has been developed. The proposed method estimates translational motion from low-resolution 2D MR image navigators acquired at each heartbeat and 3D nonrigid respiratory motion between different respiratory bins from the CMRA data itself. Estimated motion is used for correcting the CMRA as well as the emission and attenuation PET data sets to the same respiratory position. The CMRA approach was studied in 10 healthy subjects and compared for both left and right coronary arteries (LCA, RCA) against a reference scan with diaphragmatic navigator gating and tracking. The PET-CMRA approach was tested in 5 oncology patients with (18) F-FDG myocardial uptake. PET images were compared against uncorrected and gated PET reconstructions.RESULTS: For the healthy subjects, no statistically significant differences in vessel length and sharpness (P > 0.01) were observed between the proposed approach and the reference acquisition with navigator gating and tracking, although data acquisition was significantly shorter. The proposed approach improved CMRA vessel sharpness by 37.9% and 49.1% (LCA, RCA) and vessel length by 48.0% and 36.7% (LCA, RCA) in comparison with no motion correction for all the subjects. Motion-corrected PET images showed improved sharpness of the myocardium compared to uncorrected reconstructions and reduced noise compared to gated reconstructions.CONCLUSION: Feasibility of a new respiratory motion-compensated simultaneous cardiac PET-CMRA acquisition has been demonstrated. Magn Reson Med, 2017. © 2017 The Authors Magnetic Resonance in Medicine published by Wiley Periodicals, Inc. on behalf of International Society for Magnetic Resonance in Medicine.

U2 - 10.1002/mrm.26690

DO - 10.1002/mrm.26690

M3 - Article

C2 - 28426162

JO - Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine

JF - Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine

SN - 1522-2594

ER -

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