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MRI Measurement of Placental Perfusion and Fetal Blood Oxygen Saturation in Normal Pregnancy and Placental Insufficiency

Research output: Chapter in Book/Report/Conference proceedingChapter

Rosalind Aughwane, Magdalena Sokolska, Alan Bainbridge, David Atkinson, Giles Kendall, Jan Deprest, Tom Vercauteren, Anna L. David, Sébastien Ourselin, Andrew Melbourne

Original languageEnglish
Title of host publicationMedical Image Computing and Computer Assisted Intervention – MICCAI 2018 - 21st International Conference, 2018, Proceedings
EditorsGabor Fichtinger, Christos Davatzikos, Carlos Alberola-López, Alejandro F. Frangi, Julia A. Schnabel
PublisherSpringer Verlag
Pages913-920
Number of pages8
Volume11071
ISBN (Print)978-3-030-00933-5
DOIs
Publication statusPublished - 2018
Event21st International Conference on Medical Image Computing and Computer Assisted Intervention, MICCAI 2018 - Granada, Spain
Duration: 16 Sep 201820 Sep 2018

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume11071 LNCS
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349

Conference

Conference21st International Conference on Medical Image Computing and Computer Assisted Intervention, MICCAI 2018
CountrySpain
CityGranada
Period16/09/201820/09/2018

King's Authors

Abstract

The placenta is essential for successful pregnancy outcome. Inadequate placenta development leads to poor placental perfusion and placental insufficiency, responsible for one third of antenatal stillbirths. Current imaging modalities provide poor clinical assessment of placental perfusion and pregnancy outcome. In this work we propose a technique to estimate the vascular properties of retro-placenta myometrial and placental perfusion. The fetal blood saturation is a relative unknown, thus we describe a method to simultaneously estimate the fetal blood volume in addition to the fetal blood T2 relaxation time from which we can estimate this parameter. This information may prove useful for predicting if and when a placenta will fail, and thus when a small baby must be delivered to have the best neurological outcome. We report differences in vascular compartments and saturation values observed between 5 normal pregnancies, and two complicated by placental insufficiency.

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