Murine models of bone sarcomas

Camille Jacques, Nathalie Renema, Benjamin Ory, Carl R. Walkley, Agamemnon E. Grigoriadis, Dominique Heymann*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

10 Citations (Scopus)


This chapter describes the procedures for inducing bone sarcoma in mice. Two models based on inoculation of cancer cells in paraosseous and intraosseous site will be described. In addition to providing technical aspects of anesthesia and surgical options, key information of cell preparation and postoperative follow-up will be discussed.

Original languageEnglish
Title of host publicationMethods in Molecular Biology
PublisherHumana Press Inc
Number of pages12
Publication statusPublished - 1 Jan 2019

Publication series

NameMethods in Molecular Biology


  • Bone sarcoma
  • Cell-injection
  • Chondrosarcoma
  • Ewing sarcoma
  • Genetically-engineered mouse models
  • Murine preclinical models
  • Osteosarcoma


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