TY - JOUR
T1 - Neural Marker of Habituation at 5 Months of Age Associated with Deferred Imitation Performance at 12 Months
T2 - A Longitudinal Study in the UK and The Gambia
AU - The BRIGHT Study Team
AU - Katus, Laura
AU - Milosavljevic, Bosiljka
AU - Rozhko, Maria
AU - McCann, Samantha
AU - Mason, Luke
AU - Mbye, Ebrima
AU - Touray, Ebou
AU - Moore, Sophie E.
AU - Elwell, Clare E.
AU - Lloyd-Fox, Sarah
AU - de Haan, Michelle
N1 - Funding Information:
Funding: This research project is funded by the Bill and Melinda Gates Foundation Grants OPP1061089 and OPP1127625. The Nutrition Theme at MRCG is supported by the Medical Research Council (MRC) and the Department for International Development (DFID) under the MRC/DFID Concordat agreement (MRC Programme MC-A760-5QX00). This work was further supported by a Child Health Research CIO PhD Studentship and an ESRC Postdoctoral Fellowship to L.K., grant number Postdoctoral Fellowship ES/T008644/1. B.M. is supported by an Economic and Social Research Council (ESRC) Secondary Data Analysis Initiative Grant G110102. S.E.M. and S.M. are supported by a Wellcome Trust Senior Research Fellowship 220225/Z/20/Z. S.L.-F. is supported by a UKRI Future Leaders Fellowship, grant number UKRI UKRI Future Leaders Fellowship MR/S018425/1. This work is supported by the NIHR GOSH BRC. The views expressed are those of the author(s) and not necessarily those of the NHS, the NIHR or the Department of Health.
Publisher Copyright:
© 2022 by the authors. Licensee MDPI, Basel, Switzerland.
PY - 2022/7
Y1 - 2022/7
N2 - Across cultures, imitation provides a crucial route to learning during infancy. However, neural predictors which would enable early identification of infants at risk of suboptimal developmental outcomes are still rare. In this paper, we examine associations between ERP markers of habituation and novelty detection measured at 1 and 5 months of infant age in the UK (n = 61) and rural Gambia (n = 214) and infants’ responses on a deferred imitation task at 8 and 12 months. In both cohorts, habituation responses at 5 months significantly predicted deferred imitation responses at 12 months of age in both cohorts. Furthermore, ERP habituation responses explained a unique proportion of variance in deferred imitation scores which could not be accounted for by a neurobehavioural measure (Mullen Scales of Early Learning) conducted at 5 months of age. Our findings highlight the potential for ERP markers of habituation and novelty detection measured before 6 months of age to provide insight into later imitation abilities and memory development across diverse settings.
AB - Across cultures, imitation provides a crucial route to learning during infancy. However, neural predictors which would enable early identification of infants at risk of suboptimal developmental outcomes are still rare. In this paper, we examine associations between ERP markers of habituation and novelty detection measured at 1 and 5 months of infant age in the UK (n = 61) and rural Gambia (n = 214) and infants’ responses on a deferred imitation task at 8 and 12 months. In both cohorts, habituation responses at 5 months significantly predicted deferred imitation responses at 12 months of age in both cohorts. Furthermore, ERP habituation responses explained a unique proportion of variance in deferred imitation scores which could not be accounted for by a neurobehavioural measure (Mullen Scales of Early Learning) conducted at 5 months of age. Our findings highlight the potential for ERP markers of habituation and novelty detection measured before 6 months of age to provide insight into later imitation abilities and memory development across diverse settings.
KW - cross-cultural
KW - deferred imitation
KW - event-related potentials
KW - habituation
KW - novelty detection
UR - http://www.scopus.com/inward/record.url?scp=85133529931&partnerID=8YFLogxK
U2 - 10.3390/children9070988
DO - 10.3390/children9070988
M3 - Article
AN - SCOPUS:85133529931
SN - 2227-9067
VL - 9
JO - Children
JF - Children
IS - 7
M1 - 988
ER -