Neuroimaging and Genetics of the Acute and Chronic Effects of Cannabis

R. Martín-Santos; J. A. de Souza Crippa; S. Bhattacharyya

doi:10.1016/B978-0-12-800756-3.00040-5

Neuroimaging and Genetics of the Acute and Chronic Effects of Cannabis

R. Martín-Santos^*, J. A. de Souza Crippa, S. Bhattacharyya

^*Corresponding author for this work

Psychosis Studies

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Abstract

Neuroimaging research has made a major contribution to our understanding of the biological bases of mental disorders and addiction. With the growing concern about cannabis use, the number of human studies using neuroimaging techniques to determine the effect of the substance on brain structure and function has increased significantly, as has the number of recently published reviews. In this chapter, we assess the main results of neuroimaging studies of acute and chronic cannabis use, and discuss some preliminary data regarding its genetic modulation. We also note the methodological limitations of the currently available evidence, and suggest directions for future research in the field.

Original language	English
Title of host publication	Handbook of Cannabis and Related Pathologies
Subtitle of host publication	Biology, Pharmacology, Diagnosis, and Treatment
Publisher	Elsevier Inc.
Pages	e42-e52
ISBN (Electronic)	9780128008270
ISBN (Print)	9780128007563
DOIs	https://doi.org/10.1016/B978-0-12-800756-3.00040-5
Publication status	Published - 24 Jan 2017

Keywords

Addiction
AKT1
Anxiety
Brain activation
Brain imaging
Brain perfusion
Cannabidiol
Cannabis
COMT
DAT1
Delta-9-tetrahydrocannabinol
Depression
Emotional faces processing
Environmental-genetic interaction
FMRI
Gene polymorphisms
Gray matter
Memory impairment
Neuroimaging
PET
Psychosis
Response inhibition
White matter

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10.1016/B978-0-12-800756-3.00040-5

Cite this

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abstract = "Neuroimaging research has made a major contribution to our understanding of the biological bases of mental disorders and addiction. With the growing concern about cannabis use, the number of human studies using neuroimaging techniques to determine the effect of the substance on brain structure and function has increased significantly, as has the number of recently published reviews. In this chapter, we assess the main results of neuroimaging studies of acute and chronic cannabis use, and discuss some preliminary data regarding its genetic modulation. We also note the methodological limitations of the currently available evidence, and suggest directions for future research in the field.",

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KW - Brain imaging

KW - Brain perfusion

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KW - Delta-9-tetrahydrocannabinol

KW - Depression

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KW - Gene polymorphisms

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KW - PET

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BT - Handbook of Cannabis and Related Pathologies

PB - Elsevier Inc.

ER -

Neuroimaging and Genetics of the Acute and Chronic Effects of Cannabis

Abstract

Keywords

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