Neuroimaging and Resilience Factors: Staging of the At-risk Mental State?

Renata Smieskova; Paolo Fusar-Poli; Anita Riecher-Roessler; Stefan Borgwardt

doi:10.2174/138161212799316046

Neuroimaging and Resilience Factors: Staging of the At-risk Mental State?

Renata Smieskova^*, Paolo Fusar-Poli, Anita Riecher-Roessler, Stefan Borgwardt

^*Corresponding author for this work

University of Basel

Research output: Contribution to journal › Literature review › peer-review

10 Citations (Scopus)

Abstract

Over the past decade, vulnerability-and psychosis-associated structural and functional brain abnormalities in a population at high clinical risk to develop psychosis were intensively studied. We reviewed the results from studies comparing at-risk mental state (ARMS) individuals with and without subsequent transition to psychosis. Additionally, we introduced a new concept of splitting ARMS population according to the duration of the psychosis risk syndrome and their probability to develop psychosis. Studying the ARMS individuals still vulnerable to psychosis but with lower risk to transit can disclose the possible protective - resilience factors or characteristics. Resilience, understood as ability to recover from change, can be thus applied in the early intervention for high clinical risk for psychosis individuals.

Original language	English
Article number	N/A
Pages (from-to)	416-421
Number of pages	6
Journal	Current Pharmaceutical Design
Volume	18
Issue number	4
DOIs	https://doi.org/10.2174/138161212799316046
Publication status	Published - Feb 2012

Keywords

At-risk mental state (ARMS)
transition
psychosis
resilience
magnetic resonance imaging (MRI)
ULTRA-HIGH-RISK
DORSOLATERAL PREFRONTAL CORTEX
CLINICAL HIGH-RISK
ANTERIOR CINGULATE CORTEX
SUPERIOR TEMPORAL GYRUS
SPATIAL WORKING-MEMORY
GRAY-MATTER VOLUME
1ST-EPISODE SCHIZOPHRENIA
LIKELIHOOD ESTIMATION
DEVELOPING PSYCHOSIS

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@article{475e50cc923245f28d7d098196af24a1,

title = "Neuroimaging and Resilience Factors: Staging of the At-risk Mental State?",

abstract = "Over the past decade, vulnerability-and psychosis-associated structural and functional brain abnormalities in a population at high clinical risk to develop psychosis were intensively studied. We reviewed the results from studies comparing at-risk mental state (ARMS) individuals with and without subsequent transition to psychosis. Additionally, we introduced a new concept of splitting ARMS population according to the duration of the psychosis risk syndrome and their probability to develop psychosis. Studying the ARMS individuals still vulnerable to psychosis but with lower risk to transit can disclose the possible protective - resilience factors or characteristics. Resilience, understood as ability to recover from change, can be thus applied in the early intervention for high clinical risk for psychosis individuals.",

keywords = "At-risk mental state (ARMS), transition, psychosis, resilience, magnetic resonance imaging (MRI), ULTRA-HIGH-RISK, DORSOLATERAL PREFRONTAL CORTEX, CLINICAL HIGH-RISK, ANTERIOR CINGULATE CORTEX, SUPERIOR TEMPORAL GYRUS, SPATIAL WORKING-MEMORY, GRAY-MATTER VOLUME, 1ST-EPISODE SCHIZOPHRENIA, LIKELIHOOD ESTIMATION, DEVELOPING PSYCHOSIS",

author = "Renata Smieskova and Paolo Fusar-Poli and Anita Riecher-Roessler and Stefan Borgwardt",

year = "2012",

month = feb,

doi = "10.2174/138161212799316046",

language = "English",

volume = "18",

pages = "416--421",

journal = "Current Pharmaceutical Design",

issn = "1381-6128",

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TY - JOUR

T1 - Neuroimaging and Resilience Factors

T2 - Staging of the At-risk Mental State?

AU - Smieskova, Renata

AU - Fusar-Poli, Paolo

AU - Riecher-Roessler, Anita

AU - Borgwardt, Stefan

PY - 2012/2

Y1 - 2012/2

N2 - Over the past decade, vulnerability-and psychosis-associated structural and functional brain abnormalities in a population at high clinical risk to develop psychosis were intensively studied. We reviewed the results from studies comparing at-risk mental state (ARMS) individuals with and without subsequent transition to psychosis. Additionally, we introduced a new concept of splitting ARMS population according to the duration of the psychosis risk syndrome and their probability to develop psychosis. Studying the ARMS individuals still vulnerable to psychosis but with lower risk to transit can disclose the possible protective - resilience factors or characteristics. Resilience, understood as ability to recover from change, can be thus applied in the early intervention for high clinical risk for psychosis individuals.

AB - Over the past decade, vulnerability-and psychosis-associated structural and functional brain abnormalities in a population at high clinical risk to develop psychosis were intensively studied. We reviewed the results from studies comparing at-risk mental state (ARMS) individuals with and without subsequent transition to psychosis. Additionally, we introduced a new concept of splitting ARMS population according to the duration of the psychosis risk syndrome and their probability to develop psychosis. Studying the ARMS individuals still vulnerable to psychosis but with lower risk to transit can disclose the possible protective - resilience factors or characteristics. Resilience, understood as ability to recover from change, can be thus applied in the early intervention for high clinical risk for psychosis individuals.

KW - At-risk mental state (ARMS)

KW - transition

KW - psychosis

KW - resilience

KW - magnetic resonance imaging (MRI)

KW - ULTRA-HIGH-RISK

KW - DORSOLATERAL PREFRONTAL CORTEX

KW - CLINICAL HIGH-RISK

KW - ANTERIOR CINGULATE CORTEX

KW - SUPERIOR TEMPORAL GYRUS

KW - SPATIAL WORKING-MEMORY

KW - GRAY-MATTER VOLUME

KW - 1ST-EPISODE SCHIZOPHRENIA

KW - LIKELIHOOD ESTIMATION

KW - DEVELOPING PSYCHOSIS

U2 - 10.2174/138161212799316046

DO - 10.2174/138161212799316046

M3 - Literature review

SN - 1381-6128

VL - 18

SP - 416

EP - 421

JO - Current Pharmaceutical Design

JF - Current Pharmaceutical Design

IS - 4

M1 - N/A

ER -

Neuroimaging and Resilience Factors: Staging of the At-risk Mental State?

Abstract

Keywords

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